What does that mean?
Like any group of humans, there are power structures and edge cases that can lead to horrific outcomes. Giving the person that posted the warning the benefit of the doubt, I think what they are saying is that "Rationalist does not necessarily mean positive for humanity, nor even no harm for humanity". This holds for all religions and religion-like movements, of which Rationalism, in this sense, is one.
Edit: though I don't want to diminish that this specific group is a cult with classical cult techniques like sleep deprivation and with the disastrous consequences often associated with cults.
> They claim to practice unihemispheric sleep (UHS), a form of sleep deprivation intended to "jailbreak" the mind, which they believe can enhance their commitment to their cause.[
Because it uses the language and thinking patterns of the Rationalists, it serves as a strong indoctrination tool. The site itself isn't bad but, as someone who flirted with those communities as a result of the site, I think the warning is deserved.
or, if you don't buy into the "they're all the same" arguments, at least beware of the arguments against utilitarianism https://en.wikipedia.org/wiki/Utilitarianism
>Writing in Asterisk, a magazine related to effective altruism, Ozy Brennan criticized Gebru's and Torres's grouping of different philosophies as if they were a "monolithic" movement. Brennan argues Torres has misunderstood these different philosophies, and has taken philosophical thought experiments out of context.[21] Similarly, Oliver Habryka of LessWrong has criticized the concept, saying: "I've never in my life met a cosmist; apparently I'm great friends with them. Apparently, I'm like in cahoots [with them]."
The people that coined TESCREAL seem to not really be related to rationalists, and seem to have coined a term for "those vaguely related ideas from people that do some stuff we consider wrong and we consider bad". "Evil people from San Francisco" could work just as well I think.
And wait, shouldn't I beware arguments for utilitarianism rather than against? If that's what you meant yeah I agree, especially pushed to the extreme it leads you in very weird places.
You should beware of bad utilitarian arguments though, which is where you often get the real "gotta break a few eggs to make an omelette" kind of arguments that justify all manners of atrocity in service of some narrow hypothetical future good.
Like when Marc Andreessen says we should consider anyone who would do something to slow down or regulate AI advancement murderers of future humans. Bad utilitarianism right there.
Proper utilitarians are concerned with the net difference between all positive and negative consequences of actions.
Like, sure, sometimes you get popular nonsense like recovered memories or accidental fires can't be as hot as intentional fires or shaken-baby syndrome or bite-mark analysis. But a lot of times, everyone isn't wrong and you've just overlooked something critical or misdefined the problem.
Harry Potter and the Methods of Rationality is worth a read.
Or a listen: https://hpmorpodcast.com/?page_id=56
And like, I'm not a writing snob. I read fanfic by amateur authors. But HPMOR just doesn't do much of anything interesting.
Aha: "identity". You nailed the misgivings I couldn't articulate. Thank you.
The claim being made is that due to cascading decay of a secondary metabolite that does a lot of the work producing the clinical effect, caffeine elimination is a much more linear, slow process that only reaches half effect at around 10 hours and 1/4 effect at 17 hours, 1/8 effect at 23 hours.
Still decaf only. Has been a pretty positive change for me. Kicked the soda habit completely. Sleep is better. I find I’m even all day. I generally only get tired when I’m bored.
But the real question is: does it taste as good as espresso?
Coffee is an acquired taste, I think. People conditions themselves to like the bitter taste of coffee over time. I remember hating the taste of coffee (or beer, for example) in childhood.
I've not gotten that kind of profile out of anything but fairly-expensive beans roasted within the last couple of weeks, though. I've never seen it out of even mid-priced beans, nor anything nationally distributed. It's practically a totally different drink from what you get if you ask for a coffee in most contexts.
Iced coffee and cold brew are also fairly different. I find middling beans can make a much milder and more pleasant cold brew coffee than hot. Tiny (like, a teaspoon) splash of cream or milk and it takes the bitter edge all but completely off, to my taste anyway.
Good beans will last more than 2 weeks, but yes—just as you wouldn't judge all sushi based on gas station sushi, we shouldn't judge coffee based on months-old pre-ground grocery store roasts.
I wouldn't be surprised if all tastes are essentially "acquired".
Douglas Adams nailed the quality of tea from a vending machine, "almost, but not quite, entirely unlike tea", and that era of coffee machines weren't much better at coffee.
I found the need I really needed satisfied was a warm cup of something to curl my hands around in the morning, and they all worked after I let them. ymmv.
I don’t know where you live, but in Italy it’s extremely difficult to find a good espresso; you must go in "specialty coffee" places to taste real coffee, as all the bars use cheap coffee that tastes burnt. Ironically, it’s a country that takes pride in its coffee "tradition" but doesn’t know what coffee tastes like. The experience is the same in France, without the "tradition" thing.
sips half cup
BASED
Dopamine and Noradrenaline
For dopamine its the competitive for the adenosine part of the dopamine heretodimer....meaning it prevents adenosine from binding and closing the dopamine receptor....
I use the effect on both dopamine and noradrenaline to assist in controlling my ADHD via more herb based means....
But author is yes correct that the metabolism of caffeine in how it breaks down does make the half life of its effects longer than 5 hours...I combine my dose with green tea ECGC which gives me a good focus boost of 12-16 hours...
It looks like pharmacokinetics (ie how long caffeine stays in blood) is what's been studied mostly, and that's where the 5h timeline is coming from. I couldn't find papers on the timeline of pharmacodynamics of caffeine (how long it has effects).
That's an interesting gap this article is underlining!
It also has neuro-protective effects if you're an older gentleman.
I find the listed side effects don’t happen for me besides occasional flush/blush. Which at my age is more like youthful vigor.
Caffeine is is 1,3,7-trimethylxanthine, pentoxyfylline is 3,7-dimethyl-1-(5-oxohexyl)xanthine.
Good effects are: sustained mental clarity, focus and energy with a smoother more stable baseline than caffeine’s bursty performance; good sleep, but strangely you can also stay up, if you prefer; feeling similar to “after exercise”. Half life is listed as under 1 hour, but beneficial effects can be felt for half a day after 400mg (a standard dose). So maybe there’s something like metabolite dynamics occurring here too.
This ends my erowid/hive style “trip/nootropic” report ;)
I'm not a biologist, but I'm under the impression that your body uses the heuristic of "the more acutely a neurotransmitter is suddenly flooded into our system, the more of a homeostatic counter-response we're going to launch in the form of things like dopamine downregulation (etc, depending upon what neurutransmitter we're talking about)".
I'm not entirely sure this is true, but it seems to be corroborated by other researchers (e.g. Anna Lembke in her book Dopamine Nation, which isn't about caffeine though).
This is why substances like theacrine claim to offer even less tolerance than paraxanthine: it has a super gradual adenosine-blocking curve, with super long half-life (like 12-16 hours, IIRC). So when you take one theacrine, you won't notice it for hours, but its effects will last longer than one day (though I forget what its interaction with sleep is supposed to be?).
uticus•1h ago
Biochemistry is rarely a one-and-done event it would seem.