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CRISPR tech selectively shreds cancer cells, including "undruggable" cancers

https://innovativegenomics.org/news/crispr-technique-selectively-shreds-cancer-cells/
535•gmays•6h ago•140 comments

I Am Not a Reverse Centaur

https://blog.miguelgrinberg.com/post/i-am-not-a-reverse-centaur
199•ibobev•3h ago•135 comments

Swift at Apple: Migrating the TrueType Hinting Interpreter

https://www.swift.org/blog/migrating-truetype-hinting-to-swift/
35•DASD•1h ago•12 comments

How to setup a local coding agent on macOS

https://ikyle.me/blog/2026/how-to-setup-a-local-coding-agent-on-macos
148•kkm•3h ago•51 comments

Malware developers added nuclear and biological weapons text to to their spyware

https://twitter.com/jsrailton/status/2064661778978533571
206•marc__1•1d ago•140 comments

Pirates, a naval warfare game inspired by Sid Meier's Pirates

https://piwodlaiwo.github.io/pirates/
129•iweczek•4h ago•55 comments

Mmorpg World of ClaudeCraft, vibe coded with Fable 5

https://worldofclaudecraft.com/
10•beatthatflight•54m ago•2 comments

Slightly reducing the sloppiness of AI generated front end

https://envs.net/~volpe/blog/posts/reduce-slop.html
143•FergusArgyll•6h ago•97 comments

Palantir loses legal challenge against Swiss investigative magazine

https://www.ft.com/content/7ffcace7-9dc0-4e7e-9912-895ac073f979
34•sschueller•49m ago•2 comments

Launch HN: BitBoard (YC P25) – Analytics Workspace for Agents

https://bitboard.work/
28•arcb•4h ago•11 comments

"Don't You Just Upload It to ChatGPT?"

https://correresmidestino.com/dont-you-just-upload-it-to-chatgpt/
190•speckx•3h ago•165 comments

Where Did Earth Get Its Oceans? Maybe It Made Them Itself

https://www.quantamagazine.org/where-did-earth-get-its-oceans-maybe-it-made-them-itself-20260612/
86•ibobev•5h ago•50 comments

A PDF that changes based on how its read

https://sgaud.com/texts/pdf
100•SarthakGaud•4h ago•54 comments

Introduction to UEFI HTTP(s) Boot with QEMU/OVMF

https://blog.yadutaf.fr/2026/06/12/introduction-to-uefi-https-boot-qemu-ovmf/
59•jtlebigot•6h ago•17 comments

Cosmodial Sky Atlas

https://killedbyapixel.github.io/Cosmodial/
22•memalign•3h ago•1 comments

There Is Life Before Main in Rust

https://grack.com/blog/2026/06/11/life-before-main/
53•mmastrac•1d ago•13 comments

A dumpster arrived behind my university's library

https://yalereview.org/article/sheila-liming-the-end-of-books
142•mooreds•7h ago•120 comments

Maxproof

https://arxiv.org/abs/2606.13473
121•ilreb•9h ago•10 comments

Can I Buy Your KV Cache?

https://arxiv.org/abs/2606.13361
5•MediaSquirrel•1h ago•4 comments

If you are asking for human attention, demonstrate human effort

https://tombedor.dev/human-attention-and-human-effort/
1438•jjfoooo4•22h ago•450 comments

Hazel (YC W24) Is Hiring a Full Stack Engineer

https://www.ycombinator.com/companies/hazel-2/jobs/3epPWgu-full-stack-engineer-ts-sci
1•augustschen•8h ago

A Call to Action: Stop the FCC's KYC Regime

https://blog.lopp.net/call-to-action-stop-the-fcc-kyc-regime/
295•FergusArgyll•6h ago•191 comments

Show HN: StackScope – I crawled over 40k indie launches to see what they ship

https://stackscope.dev/
35•datafreak_•6h ago•12 comments

WASI 0.3

https://bytecodealliance.org/articles/WASI-0.3
211•mavdol04•7h ago•83 comments

You can power on a Mac remotely

https://www.jeffgeerling.com/blog/2026/power-on-your-mac-remotely/
28•speckx•5h ago•18 comments

Law Enforcement's "Warrior" Problem (2015)

https://harvardlawreview.org/forum/vol-128/law-enforcements-warrior-problem/
74•bookofjoe•4h ago•59 comments

Looking Forward to Postgres 19: It's About Time

https://www.pgedge.com/blog/looking-forward-to-postgres-19-its-about-time
112•xngbuilds•4h ago•33 comments

Most Beautiful Will Ever Made (1936)

https://paperspast.natlib.govt.nz/newspapers/DOM19360307.2.43
9•cf100clunk•3h ago•1 comments

A jacket that harvests drinking water from the air

https://news.utexas.edu/2026/06/11/this-jacket-pulls-drinking-water-from-thin-air/
154•ilreb•22h ago•96 comments

Encrypted Spaces An architecture for collaborative applications

https://encryptedspaces.org/
54•_____k•9h ago•7 comments
Open in hackernews

Extending a Language – Writing Powerful Macros in Scheme

https://mnieper.github.io/scheme-macros/README.html
92•textread•1y ago

Comments

neilv•1y ago
A few formatting changes might make this advanced example easier to understand:

    (define-syntax trace-let
      (syntax-rules ()
        [(trace-let name ([var expr] ...) body1 ... body2)
         (let f ([depth 0] [var expr] ...)
           (define name
             (lambda (var ...)
               (f (+ depth 1) var ...)))
           (indent depth)
           (display "(")
           (display 'name)
           (begin
             (display " ")
             (display var))
           ...
           (display ")")
           (newline)
           (call-with-values
               (lambda ()
                 body1 ... body2)
             (lambda val*
               (indent depth)
               (fold-left
                (lambda (sep val)
                  (display sep)
                  (display val)
                  " ")
                "" val*)
               (newline)
               (apply values val*))))]))
The biggest one is to make the rule template pattern variables all-uppercase. I also made a few other tweaks, including using indentation a little more, and naming the named-`let` variable as "loop" (I usually name it `loop` or prefix the name with `loop-` if there's more than one):

    (define-syntax trace-let
      (syntax-rules ()
        ((trace-let NAME ((VAR EXPR) ...) BODY1 ... BODY2)
         (let loop ((depth 0)
                    (VAR   EXPR) ...)
           (define NAME
             (lambda (VAR ...)
               (loop (+ depth 1) VAR ...)))
           (indent depth)
           (display "(")
           (display (quote NAME))
           (begin (display " ")
                  (display VAR)) ...
           (display ")")
           (newline)
           (call-with-values (lambda ()
                               BODY1 ... BODY2)
             (lambda val*
               (indent depth)
               (fold-left (lambda (sep val)
                            (display sep)
                            (display val)
                            " ")
                          ""
                          val*)
               (newline)
               (apply values val*)))))))
Incidentally, all-uppercase Scheme pattern variables is one of the all-time best uses of all-uppercase in any language. Second only to all-uppercase for the C preprocessor, where a preprocessor macro can introduce almost arbitrary text. Using all-uppercase for constants in some language that has constants, however, is an abomination.

(My suspicion of why Java did all-caps is that they were developing a language for embedded systems developers who were currently using C and C++, and they wanted to make it superficially look similar, even though it was an entirely different language. And then, ironically, the language ended up being used mostly by the analogue of a very different developer of the time: corporate internal information systems developers, who, as a field, didn't use anything like C. It's too late to save Java, but to all other language and API developers, please stop the insanity of all-caps constants, enum values, etc. It's not the most important thing that needs to jump out from the code above all other things.)

Y_Y•1y ago
FWIW, all-caps makes this look much worse to me. I understand that people like things like Hungarian notation, arrows over vector names, and shouting Common Lisp symbols. I understand the argument that it can make reading easier. I just can't appreciate that benefit, and it seems to me an ugly hack which obscures the abstract and general symbolic manipulation going on.

This is all highly subjective of course, de gustibus non disputandem.

neilv•1y ago
You mean aesthetically, in that interspersed all-caps makes the code visually less soothingly sensual?

I can sympathize, but let me make a non-aesthetic argument...

In large blocks of code, with all-caps, you can see at a glance where all the template substitutions are happening, and also instantly know as you're reading code what are variables and what are template substitutions?

I'm asking because one of my realizations in recent years is that not everyone reads or sees code the same way.

For example, maybe some people are stronger "visual" and some people are stronger "verbal".

For another example of a different in how people perceive and think, some people can visualize an object in their mind almost as if they're looking at it, but other people can only know and describe what it looks like without bringing a visual of it into their head.

With the benefit of the all-caps, I can glance at this and immediately see much of the structure of the template. Without all-caps, I'd have to work harder to find all the pattern variables, and the structure would be obscured.

For a bit kludgy practical matter, as I'm quickly looking at pieces of code in a template, with all-caps, I can look at a fragment of code in isolation and know what are and aren't pattern variables. Without that, I have to go read the top of the template clause (and read through any syntactic scopes of `let-syntax`) and get that in my head, until I get to the fragment of code I originally wanted to look at.

IDE support can make this unnecessary, with a hypothetical great IDE, with familiar syntax coloring. But still, if there is one thing that all-caps should be reserved for, it's something like this.

With all-caps, your code can be sensual, and the jolting all-caps bits are look out, potentially arbitrary code gets pasted into here.

mnemenaut•1y ago
https://github.com/rogerturner/scheme-macros/blob/main/examp... shows stepwise development of a trace-let [the `(example: (fn arg) => result)` forms are tests - see check-examples library]
Y_Y
•
1y ago
Since you asked, my objection is both aesthetic and semantic, though I was really referring to the semantic part above.

I think you've hit the nail on the head with this visual vs. verbal distinction.

I can add a few clarifying details. I don't use IDEs as much as basic text editors maybe with highlighting, and I try not to rely on any fancy features. It does worry me that the allcaps use you describe is (afaik) not known to the editor or interpreter, so if you make a mistake or the symbol gets out of sync with its meaning (re: pattern variables) you may have a false signal. Finally I'll say that in the end I can't suggest a good way to treat these special variables, and so maybe I don't get it, or tastes like mine would be better served by a different formalism for macros.