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Transformer: The Deep Chemistry of Life and Death

https://nick-lane.net/books/transformer-the-deep-chemistry-of-life-and-death/
51•mitchbob•3d ago

Comments

qoez•11h ago
Don't love when books try to SEO optimize by hijacking another more popular term (the transformer which has nothing to do with this). Just pick a nice classy title instead. Seems like an interesting read though.
profchemai•10h ago
I've read this book, I don't think this was the case. I think the name was made in good-faith. It's "transformer" because it involves transformations of molecules involved in life (reactions, enzymes, metabolism). The author has used this term before 2022.

The same argument could be made for the transformer paper: hijacking a nostalgia pop-culture name to name a deep learning bi-linear operator. Many papers are guilty of this, some just become very influencial.

amelius•10h ago
Indeed. This transformer has nothing to do with electrical currents and voltages.
20after4•5h ago
But it actually does. Watch the video embedded on the page, it actually has everything to do with electrical currents.
bornfreddy•8h ago
That... doesn't make sense? If anything, using a popular term would be a disadvantage wrt. SEO, because now they need to compete against many many many unrelated websites.
emmelaich•1h ago
Yep it wasn't about Lou Reed's seminal album. https://en.wikipedia.org/wiki/Transformer_(Lou_Reed_album)
pchristensen•8h ago
Context: I've read this and The Vital Question and watched several interviews with Nick Lane, so a lot of his ideas have blended together in my mind. A lot of the detail in this book went over my head, but it was well written enough to overcome my shortcoming in biochemistry. Similar in depth to Siddhartha Mukherjee's Song of the Cell and The Gene.

This book was a fascinating walk through evolutionary history and the way that different organisms handle energy, and how earlier, less efficient metabolic paths were limited but sufficient to bootstrap the much more efficient and flexible Kreb's cycle. I remember the term and the loop diagram from high school biology, but to actually dive into the elegant chemical pathways felt like discovering the rocket equation or the path from radioactivity to atomic bombs. If you're at all interested in Biology or Chemistry, I highly recommend this book.

robwwilliams•4h ago
To try to stay in topic: Nick Lane is a top tier biochemist who can even make the Krebs cycle riveting (aka the citric acid cycle: https://en.wikipedia.org/wiki/Citric_acid_cycle ) His book “Power, Sex, and Suicide” is probably a better book to start with.

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