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Start all of your commands with a comma

https://rhodesmill.org/brandon/2009/commands-with-comma/
56•theblazehen•2d ago•11 comments

OpenCiv3: Open-source, cross-platform reimagining of Civilization III

https://openciv3.org/
637•klaussilveira•13h ago•188 comments

The Waymo World Model

https://waymo.com/blog/2026/02/the-waymo-world-model-a-new-frontier-for-autonomous-driving-simula...
935•xnx•18h ago•549 comments

What Is Ruliology?

https://writings.stephenwolfram.com/2026/01/what-is-ruliology/
35•helloplanets•4d ago•30 comments

How we made geo joins 400× faster with H3 indexes

https://floedb.ai/blog/how-we-made-geo-joins-400-faster-with-h3-indexes
113•matheusalmeida•1d ago•28 comments

Jeffrey Snover: "Welcome to the Room"

https://www.jsnover.com/blog/2026/02/01/welcome-to-the-room/
13•kaonwarb•3d ago•11 comments

Unseen Footage of Atari Battlezone Arcade Cabinet Production

https://arcadeblogger.com/2026/02/02/unseen-footage-of-atari-battlezone-cabinet-production/
45•videotopia•4d ago•1 comments

Show HN: Look Ma, No Linux: Shell, App Installer, Vi, Cc on ESP32-S3 / BreezyBox

https://github.com/valdanylchuk/breezydemo
222•isitcontent•13h ago•25 comments

Monty: A minimal, secure Python interpreter written in Rust for use by AI

https://github.com/pydantic/monty
214•dmpetrov•13h ago•106 comments

Show HN: I spent 4 years building a UI design tool with only the features I use

https://vecti.com
324•vecti•15h ago•142 comments

Sheldon Brown's Bicycle Technical Info

https://www.sheldonbrown.com/
374•ostacke•19h ago•94 comments

Hackers (1995) Animated Experience

https://hackers-1995.vercel.app/
478•todsacerdoti•21h ago•237 comments

Microsoft open-sources LiteBox, a security-focused library OS

https://github.com/microsoft/litebox
359•aktau•19h ago•181 comments

Show HN: If you lose your memory, how to regain access to your computer?

https://eljojo.github.io/rememory/
278•eljojo•16h ago•165 comments

An Update on Heroku

https://www.heroku.com/blog/an-update-on-heroku/
407•lstoll•19h ago•273 comments

Vocal Guide – belt sing without killing yourself

https://jesperordrup.github.io/vocal-guide/
17•jesperordrup•3h ago•10 comments

Dark Alley Mathematics

https://blog.szczepan.org/blog/three-points/
85•quibono•4d ago•21 comments

PC Floppy Copy Protection: Vault Prolok

https://martypc.blogspot.com/2024/09/pc-floppy-copy-protection-vault-prolok.html
57•kmm•5d ago•4 comments

Delimited Continuations vs. Lwt for Threads

https://mirageos.org/blog/delimcc-vs-lwt
27•romes•4d ago•3 comments

How to effectively write quality code with AI

https://heidenstedt.org/posts/2026/how-to-effectively-write-quality-code-with-ai/
245•i5heu•16h ago•193 comments

Was Benoit Mandelbrot a hedgehog or a fox?

https://arxiv.org/abs/2602.01122
14•bikenaga•3d ago•2 comments

Introducing the Developer Knowledge API and MCP Server

https://developers.googleblog.com/introducing-the-developer-knowledge-api-and-mcp-server/
54•gfortaine•11h ago•22 comments

I spent 5 years in DevOps – Solutions engineering gave me what I was missing

https://infisical.com/blog/devops-to-solutions-engineering
143•vmatsiiako•18h ago•64 comments

I now assume that all ads on Apple news are scams

https://kirkville.com/i-now-assume-that-all-ads-on-apple-news-are-scams/
1061•cdrnsf•22h ago•438 comments

Learning from context is harder than we thought

https://hy.tencent.com/research/100025?langVersion=en
179•limoce•3d ago•96 comments

Understanding Neural Network, Visually

https://visualrambling.space/neural-network/
284•surprisetalk•3d ago•38 comments

Why I Joined OpenAI

https://www.brendangregg.com/blog/2026-02-07/why-i-joined-openai.html
137•SerCe•9h ago•125 comments

Show HN: R3forth, a ColorForth-inspired language with a tiny VM

https://github.com/phreda4/r3
70•phreda4•12h ago•14 comments

Female Asian Elephant Calf Born at the Smithsonian National Zoo

https://www.si.edu/newsdesk/releases/female-asian-elephant-calf-born-smithsonians-national-zoo-an...
28•gmays•8h ago•11 comments

FORTH? Really!?

https://rescrv.net/w/2026/02/06/associative
63•rescrv•21h ago•23 comments
Open in hackernews

'Turbocharged' Mitochondria Power Birds' Epic Migratory Journeys

https://www.quantamagazine.org/turbocharged-mitochondria-power-birds-epic-migratory-journeys-20250519/
78•pseudolus•8mo ago

Comments

coolcase•8mo ago
Wouldn't mind some bird mitochondria!
b800h•8mo ago
Seriously, what would happen if we swapped out human mitochondria from a zygote for bird mitochondria?
jyounker•8mo ago
I don't think you'd get the same sort of effects, because a huge part of the mitochondrial regulation and function is carried out by genes and gene products from outside the mitochondria.

It would be an interesting experiment though. I'd expect that they might not live, or that the cell would function sub-optimally, but who knows, maybe the cellular machinery is highly conserved.

dejj•8mo ago
Yes. Afaik from Nick Lane’s “Oxygen” the Cytochrome Oxidase made from the mitochondrial DNA have to match the Cytochrome C made from nuclear DNA. Even slight mismatch seems to lower mitochondrial performance and is a problem why heteroplasmy (mixing of mitochondria from father and mother) seems to be selected-out.
treyd•8mo ago
Well what if you also swapped out those genes?
dejj•8mo ago
If your mitochondria have bird DNA and your nucleus has bird DNA, then you’re a bird.

There’s an easier way. A single nucleotide polymorphism (SNP) that only and rarely is observed in Japanese can extend human lifespan greatly. Flip a single base pair. This seems the most promising first step for genetically engineering humans.

dghughes•8mo ago
You'd get Kids in the Hall Chicken Lady.
mckirk•8mo ago
And some whale blood!
ljf•8mo ago
Previously posted: https://news.ycombinator.com/item?id=44051652 (1 day ago, 78 comments)
rbanffy•8mo ago
Can the entries be merged?
EGreg•8mo ago
Can they? Yes. Should they? No.
rbanffy•8mo ago
Why have two separate discussions on the same topic a day apart?
gherkinnn•8mo ago
No layman's discussion about mitochondria is complete without the In Our Time episode on just that:

https://www.bbc.co.uk/programmes/m001md34

It is one of my favourites.

londons_explore•8mo ago
What is the typical lifespan of ATP within a cell?

Are we talking milliseconds or minutes?

pfdietz•8mo ago
According to the wikipedia page on ATP, the average ATP concentration in eukaryotic cells is 1 to 10 micromols per gram.

According to https://bionumbers.hms.harvard.edu/bionumber.aspx?s=n&v=2&id... a single mammalian cell has a mass of 3 to 4 nanograms.

Google AI tells me the average rate of ATP formation in a mammalian cell is around 10 million molecules per second.

The ratio here ranges from 3 to 40 minutes.

I imagine it varies greatly depending on cell type.

eitally•8mo ago
From an exercise physiology point of view, it's generally accepted that ATP-CP powered motility is possible for only about 10 seconds (that is to say, you only store enough ATP for about 10 seconds of high intensity work -- sprinting, maximal weight lifting, etc). After that, other energy systems become dominant ... both of which create ATP but depend on either glycolysis (anaerobic) or oxidative phosphorylation (aerobic) for the process/conversion.
ck2•8mo ago
vaguely related there is a fantastic new PBS Space Time this week which suggests the "no alien life" fermi paradox may be related to how our mitochondria evolved by a series of fortunate accidents which may not be reproducible elsewhere

https://www.pbs.org/video/is-there-a-simple-solution-to-the-...

( https://www.youtube.com/watch?v=abvzkSJEhKk )