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FDA Intends to Take Action Against Non-FDA-Approved GLP-1 Drugs

https://www.fda.gov/news-events/press-announcements/fda-intends-take-action-against-non-fda-appro...
12•randycupertino•16m ago•3 comments

Tiny C Compiler

https://bellard.org/tcc/
17•guerrilla•55m ago•2 comments

SectorC: A C Compiler in 512 bytes

https://xorvoid.com/sectorc.html
132•valyala•5h ago•22 comments

The F Word

http://muratbuffalo.blogspot.com/2026/02/friction.html
63•zdw•3d ago•22 comments

Brookhaven Lab's RHIC concludes 25-year run with final collisions

https://www.hpcwire.com/off-the-wire/brookhaven-labs-rhic-concludes-25-year-run-with-final-collis...
29•gnufx•3h ago•27 comments

Speed up responses with fast mode

https://code.claude.com/docs/en/fast-mode
67•surprisetalk•4h ago•83 comments

Software factories and the agentic moment

https://factory.strongdm.ai/
108•mellosouls•7h ago•205 comments

You Are Here

https://brooker.co.za/blog/2026/02/07/you-are-here.html
7•mltvc•52m ago•1 comments

Hoot: Scheme on WebAssembly

https://www.spritely.institute/hoot/
150•AlexeyBrin•10h ago•26 comments

OpenCiv3: Open-source, cross-platform reimagining of Civilization III

https://openciv3.org/
856•klaussilveira•1d ago•263 comments

Stories from 25 Years of Software Development

https://susam.net/twenty-five-years-of-computing.html
108•vinhnx•7h ago•14 comments

Italy Railways Sabotaged

https://www.bbc.co.uk/news/articles/czr4rx04xjpo
32•vedantnair•58m ago•18 comments

The Waymo World Model

https://waymo.com/blog/2026/02/the-waymo-world-model-a-new-frontier-for-autonomous-driving-simula...
1105•xnx•1d ago•619 comments

I write games in C (yes, C)

https://jonathanwhiting.com/writing/blog/games_in_c/
151•valyala•4h ago•125 comments

First Proof

https://arxiv.org/abs/2602.05192
71•samasblack•7h ago•53 comments

Show HN: A luma dependent chroma compression algorithm (image compression)

https://www.bitsnbites.eu/a-spatial-domain-variable-block-size-luma-dependent-chroma-compression-...
16•mbitsnbites•3d ago•0 comments

Al Lowe on model trains, funny deaths and working with Disney

https://spillhistorie.no/2026/02/06/interview-with-sierra-veteran-al-lowe/
70•thelok•6h ago•13 comments

Vocal Guide – belt sing without killing yourself

https://jesperordrup.github.io/vocal-guide/
247•jesperordrup•15h ago•82 comments

Start all of your commands with a comma (2009)

https://rhodesmill.org/brandon/2009/commands-with-comma/
526•theblazehen•3d ago•196 comments

Show HN: I saw this cool navigation reveal, so I made a simple HTML+CSS version

https://github.com/Momciloo/fun-with-clip-path
35•momciloo•4h ago•5 comments

LLMs as the new high level language

https://federicopereiro.com/llm-high/
4•swah•4d ago•0 comments

Selection Rather Than Prediction

https://voratiq.com/blog/selection-rather-than-prediction/
16•languid-photic•3d ago•5 comments

Reinforcement Learning from Human Feedback

https://rlhfbook.com/
96•onurkanbkrc•9h ago•5 comments

The AI boom is causing shortages everywhere else

https://www.washingtonpost.com/technology/2026/02/07/ai-spending-economy-shortages/
198•1vuio0pswjnm7•11h ago•294 comments

72M Points of Interest

https://tech.marksblogg.com/overture-places-pois.html
40•marklit•5d ago•6 comments

A Fresh Look at IBM 3270 Information Display System

https://www.rs-online.com/designspark/a-fresh-look-at-ibm-3270-information-display-system
51•rbanffy•4d ago•12 comments

Coding agents have replaced every framework I used

https://blog.alaindichiappari.dev/p/software-engineering-is-back
265•alainrk•9h ago•438 comments

France's homegrown open source online office suite

https://github.com/suitenumerique
632•nar001•9h ago•278 comments

Unseen Footage of Atari Battlezone Arcade Cabinet Production

https://arcadeblogger.com/2026/02/02/unseen-footage-of-atari-battlezone-cabinet-production/
126•videotopia•4d ago•40 comments

Where did all the starships go?

https://www.datawrapper.de/blog/science-fiction-decline
105•speckx•4d ago•132 comments
Open in hackernews

Human Brain Cells on Chip for Sale – First biocomputing platform hits the market

https://spectrum.ieee.org/biological-computer-for-sale
50•mdp2021•8mo ago

Comments

hartator•8mo ago
This may be the shortcut to an AI 1,000 smarter than a human.
hulitu•8mo ago
> This may be the shortcut to an AI 1,000 smarter than a human.

Well, there are humans, and then, there are former US presidents. I never regarded "Hot Shots" as a documentary, but, i was young, when i first saw it.

rl3•8mo ago
>Kagan says Cortical Labs has seen strong interest from universities, startups, and government groups exploring applications in drug discovery, neurocomputation, AI acceleration, and Bitcoin mining.

Really? Bitcoin mining?

api•8mo ago
That shows that the author understands nothing about either Bitcoin or neurons.
mrWiz•8mo ago
Or that the author wanted to accurately represent what Kagan said.
UncleOxidant•8mo ago
Or Kagan doesn't?
MyPasswordSucks•8mo ago
> Kagan says Cortical Labs has seen strong interest from . . . groups exploring applications in . . . Bitcoin mining.

Einstein might see strong interest from people exploring perpetual motion machines. It doesn't mean Einstein doesn't understand physics.

__MatrixMan__•8mo ago
Writing about strong interest from a bitcoin miner says more about the miner than the author.
Jun8•8mo ago
I think this is the point-contact transistor moment for AI systems: horribly impractical and impossible to scale at cost but shows the way: https://en.m.wikipedia.org/wiki/Point-contact_transistor.

But more than just AI research, the key to unlocking biological discoveries in a massive scale will be to be able to put systems like this (and other types of very cheap but solid bio equipment) in hands of tinkerers.

chneu•8mo ago
The YouTuber "The Thought Emporium" has been working on a similar project for a few years.

https://youtu.be/bEXefdbQDjw

They run an amazing channel that covers a variety of topics. Highly recommend. The mummification video is fun.

api•8mo ago
In the Rifters trilogy by author Peter Watts this is referred to as “head cheese” because cultured neurons resemble cheese at large scale. It’s used for big powerful AIs in that series and has a role in the plot.
KingFelix•8mo ago
Is the trilogy any good? Im just about to finish blindsight
RobotCaleb•8mo ago
I really quite enjoyed it but thought it got a little weird towards the end. The initial premise is quite great
XorNot•8mo ago
Blindsight is definitely the superior novel IMO. I'd say it's probably the author's best.
darepublic•8mo ago
Human brain in a jar? Any chance of sentience if we scale this up...?
8bitsrule•8mo ago
Sure, sure, sure, sure, sure!

https://www.youtube.com/watch?v=buSR97QeCq8

femto•8mo ago
The article says:

"The first 115 units will begin shipping this summer at $35,000 each"

From Cortical's home page [1]:

"We're a revolutionary biotech firm based in Melbourne, Australia."

Melbourne is the capital city of the Australian state of Victoria.

Part VIII, Section 38, paragraph (1) of the Victorian "Human Tissue Act 1982" says:

"Subject to this section, a person shall not sell, or agree to sell, tissue (including his own tissue) or the right to take tissue from his body."

Maybe you buy the device and they throw the brain cells in for free?

[1] https://corticallabs.com/company.html

[2] https://content.legislation.vic.gov.au/sites/default/files/2...

bluesounddirect•8mo ago
The more I read the article the less i believe it . for all we know its just some pig brains smeared on some chip with some creative marketing. Bitcoin and the Music Industry pfft what b/s .
moralestapia•8mo ago
It's all nepo.

If you're in the right circle you can do illegal stuff and it will be brushed off as "the cost of innovation".

If you're in the wrong circle you might get your company shut down because you can only consume up to 500 gallons of water a month unless you apply for a special permit and last month you did 501.5 gallons, or some other crap. And the same people will say "yeah, I know it's a bit harsh but that's the cost of keeping order in society bla bla bla".

XorNot•8mo ago
The act says you can't sign an agreement for this to happen to a person.

But plenty of incidental material is recovered (e.g. fetal cord blood).

iancmceachern•8mo ago
Cadaver tissue is commonly "processed" and then used to make all kinds of medical devices. Bone and tendons are a common example for bone and joint reconstruction surgeries. I can't speak too much to Australia specifically, but because of laws like this in the US these supply chains are setup a specific wah. A good example is Allosource in Colorado. The donations are donations, in return the persons final expenses are taken care of. The company that does the processing and reselling is a non-profit. In this case no one person "sells" any part of their or other persons bodies, but the needed medical materials get to the OR.
gnabgib•8mo ago
Related:

The CL1: the first code deployable biological computer (54 points, 28 days ago, 24 comments) https://news.ycombinator.com/item?id=43909418

Melbourne startup launches 'biological computer' made of human brain cells (54 points, 3 months ago, 37 comments) https://news.ycombinator.com/item?id=43261218

Cortical Labs: "Human neural networks raised in a simulation" (89 points, 2 years ago, 126 comments) https://news.ycombinator.com/item?id=37982175

dang•8mo ago
Thanks! Is there more there here now?

https://news.ycombinator.com/item?id=43909452

gnabgib•8mo ago
Possibli it's catnip for HN :D (I think I caught the past votes/discussions)
ozten•8mo ago
How does this compare to a conventional CPU or GPU in terms of flops per second? Or does this not present a traditional architecture?
jcims•8mo ago
> “However, the real gift of this technology is not to computer science. Rather, it’s an enabling technology that allows scientists to perform experiments on a little synthetic brain.”

It’s probably not directly mappable in any reasonable way. At least not until a lot more people get their hands on it and explore the possibilities.

hulitu•8mo ago
Well, it's a flop, so it compares. /s
spwa4•8mo ago
How about: it's flopPY, every second?

Seriously brains are neither analog nor digital, they use spike-trains. Very comparable to "clockless" digital circuits. To what we use in chips, synchronized tick-based calculation: it's not comparable. Judging by human but especially animal reaction times: one way to quantify it is to say it has about 10000 flop per second. technically the human head has 2 speeds: one type of cells with 1000 synapses, that can calculate about 10 times per second (the "animal brain" or reptile brain, the cortex). And there are cells with 10000 synapses that fire on average 1 time per second (the "human brain", the neocortex), which should be roughly the same capacity. Of this network type it is known that more synapses means more accurate, more long-term planning. Faster firing means faster responses. Reptiles are stupid, but despite reptiles being cold blooded we mammals have zero chance to respond in time to an attack. It's not happening. And yes, cats have a built-in trick that gives them a fighting chance, but is only ever going to work in small animals (you need muscles powerful enough to throw yourself several body lengths into the air, and you need to be small and light enough that you survive being thrown in the air several body lengths without coordination, and land without injury. Both properties that humans, or any animal 1m or bigger will never have. And of course, that reflex is an incredible source of youtube videos)

The problem with spike trains is that it's tough to say if a zero signal means anything. On the one hand, all zeros means the cell isn't using energy, and that is incredibly efficient (nanowatt, not even multiple nanowatts). Everything about your mind is designed to almost always be all zeros. A spike means milliwatt power usage for .15-.2 seconds after the spike. Given the amount of neurons, our brain would rapidly cook itself if the average firing rate even just double, in fact that is exactly what happens with epilepsy patients.

The above calculations only apply if all zeros means the network isn't doing anything. If that assumption is wrong, you should probably multiply those figures with the temporal accuracy of the spikes, which is incredible, 3-4 nanosecond. So you'd have to multiply the figures by 300 million, at which point the human mind still is 1000 times stronger than even a full stargate deployment. That sounds incredible, but it really isn't.

If you want to see incredible figures, figure out how much calculations natural selection does for a simple ocean-based bacterial species (assuming 1 cell division = one calculation, if you assume a more reasonable 1 allele combination = 1 flop, you're another 3-5 orders of magnitude higher). Bacteria do hundreds of orders of magnitude more thinking than all humans combined.

mdp2021•8mo ago
That was very interesting. Do you have relevant reading material to recommend, good sources?
spwa4•8mo ago
This is the standard work on the subject: https://direct.mit.edu/books/edited-volume/2001/chapter-abst...
temporallobe•8mo ago
Have we learned nothing from the Borg?
banga•8mo ago
How long before they realize just ditch the life support apparatus and plug into human brains.
jcims•8mo ago
Feels like this could really help with brain-compute interfaces.

I have this pet theory that things like this will ultimately lead to a path for us to ‘feel’ our interactions with the digital domain in a way similar to our own thoughts and maybe eventually lead to a better understanding of that one hard problem.