I like Orion for its feature that lets me set the whole internet to opt-in mode for javascript. Really a beautiful default for surfing, can't recommend giving it a try enough.

Does it support SOCKS proxies now? If FoxyProxy or something like that works for it, I might give it a try. Last I checked, the browser itself only supported HTTP proxies and since Safari based it opened the Network Configuration system preferences page.

Edit: Tested on latest Orion. FoxyProxy silently does not function. You can configure a proxy, you can even enable it but it will just not use it. Still no way to use a SOCKS proxy.