https://en.wikipedia.org/wiki/List_of_tallest_people
And another was 76cm high:
But that's just guessing. The article might not even have found something profound, but a life-style effect. On the one hand, we're living long (historically speaking), on the other hand, we have unnatural habits.
It's the same as how although you can occasionally get a "natural" person over seven feet tall, it's very rare. Most really tall people have gigantism or some other form of pituitary abnormality, and I believe every recorded person to break eight feet has had such an abnormality.
It's like asking why we've never had someone with 500 IQ. There's a hard limit where anyone with enough of a mutation to enable that would probably also not survive long at all. And indeed with the height thing we see a lot of super-tall people dying younger due to cardiovascular strain and other issues. You get the picture.
The "patterns of aging" you describe are, again, definitionally just what happens when the same organs built and functioning the same way across species undergo their respective failure modes. It makes more sense for all skins to exhibit the same signs of aging if they're all just wearing out the way "skin" does, rather than being attacked by species-specific "age limiter" processes artificially enforcing lifespan limits. Why would something like skin even need to decay at all, when it's basically unrelated to aging-related death?
Which is actually a pretty good reason for something like menopause to get programmed in. A proto-human capable of getting pregnant into her 60s would produce more offspring, but if accumulated damage meant they (and she) rarely survived the pregnancy, that could be less beneficial to the family group (including numerous relatives other than direct descendants) on average than having her switch the capability off and live another generation (but not many more generations, because then there's a lot of infertile people competing for food, and your tribe only needs so much accumulated wisdom)
> Back in 1994 a study looked at every man entered into the Oxford Classical Dictionary who lived in ancient Greece or Rome. Their ages of death were compared to men listed in the more recent Chambers Biographical Dictionary. Of 397 ancients in total, 99 died violently by murder, suicide or in battle. Of the remaining 298, those born before 100BC lived to a median age of 72 years. Those born after 100BC lived to a median age of 66. (The authors speculate that the prevalence of dangerous lead plumbing may have led to this apparent shortening of life).
https://www.bbc.com/future/article/20181002-how-long-did-anc...
Just one source
By this logic, as a hedge against sudden death around ~50, the human body start cranking down the output of its diverse subsystems by then, to maximize operacional life, just like NASA engineers from time to time turn off instruments in the voyager to keep it operational against the odds. This is what we call ageing.
What limitation is our body pushing off by 'choosing' to age, instead of continuing as normal?
Edit: Regardless of the validity of the argument, I loved that comic, thanks for sharing.
So the question becomes why can't somatic cells repair themselves to be as healthy as germline cells?
So, to rejuvenate the body, you would have to find where the current state of that program is stored, and overwrite it to a younger one, as if using a debugger. So far there are two promising developments about that: Michael Levin's research about bioelectricity, and Harold Katcher's research about exosomes (he seems to have abandoned it, but other people are picking up).
https://med.stanford.edu/news/all-news/2024/08/massive-biomo...
I feel 25 years younger now. My BP and cholesterol are under control and I roll out of bed actually feeling rested (probably due to not snoring anymore).
It won’t make you feel 32 again but it might help you get rid of a lot of lingering aches and pains.
Note: I also aggressively supplemented with BPC-157, GHK-cu and TB-500 to get to where I am.
(Full protocol if you haven’t seen it is a ~30 second isometric repeated 4 to 5 times, twice per day)
Edit: I’ve not seen any other treatment published w/ peer review etc etc that demonstrates actual tendon repair. If anyone has seen others I’d love to read through the literature.
Keith Barr focused on musical technology at MXR, Alesis and eventually Spin Semiconductor. His legacy is MXR pedal effects like the Phase-90, the MidiVerb digital reverb series and the Spin FV-1 digital reverb chip.
Having lived in San Diego most of my life, I've routinely met people in their 60s doing Ironmans. When you're around that enough, it's clear the difference is training smart than simply training hard.
I also run and so far I am able to keep improving my 10K results over the last decade. Probably these aren't my best ever but there is no barrier that I can feel other than putting in the training volume.
Your toddler needs healthy parents.
I feel great when I eat clean.
I did that for about 2 years with good results. I was 240lbs. I looked big at 6’1 but had lots of fat. I snored all night long, affecting my wife’s sleep as well. About 1 year in I got on trt. Huge changes as far as energy levels, sex drive and confidence. Numbers soared at the gym but I was still 240lbs. Still stress eating after 8pm, easily 1200 calories in sugar a night.
In January I got on Glp-1 and am now 209lbs at 46 years old with a 405lb bench. I just stopped eating after 6pm on it. Weight came pouring off. I never experienced any of the side effects people mention. I can eat a whole large pizza if I want without issues, i just don’t.
I’ve since upped the testosterone im on so one can fairly say im on steroids (i am) plus I am an aggressive user of various peptides. I get my blood work done at regular intervals and feel good.
I just decided to take control of my body and do what works for me and not worry about what the medical establishment tells me to do but to do it with proper insight via regular blood tests.
Just got back from a family vacation and after the pool one day my wife asked if I knew that everyone stared at me when I walk past. Felt good. Funny thing is that at 6’1, 209lbs im not that big, im just lean whereas most people are overweight.
I don’t recommend my regime to anyone i just recommend throwing away preconceived notions of what you can and shouldn’t do and to get after being the you that you are proud of.
While you might not be able to get to the exact same level of fitness as if you had trained for years, I think you can get fairly close. And without a doubt, you can drastically improve from wherever you’re starting.
I do have a question: is there benefits in pushing harder if my goal is just health, or should I keep my training as is to limit injuries?
I'm 36, so not related to the article yet.
It is always 20 for me. 4 sets. I am 64. I used to do 30 when I was a teen but I was much lighter then. also lots of swimming, cycling, hiking canoeing etc. etc
Re my health, I kinda feel like Mad Magazine's Alfred E. Neuman: "What, me worry?" I worry more about the state of the US than I do about my own health. We're all going to die - I've lived a lot longer than many people. I've outlived Steve Jobs by 5 years at this point. Suck it, Steve! (And Jim Morrison? 34 years. Looooser!)
If you do cardio - even just walking/hiking - and weight training, you're going to be healther than 95% of people, and live longer with better quality of life. It's not that difficult.
As you age, if you're reasonably sane, you start letting go of the idea that you can or should live forever.
I'm (only?) 44, and I still can't quite make peace with the idea of death. I'm not really afraid of it, but I can't stand the idea that I'm going to miss out on so many cool events in the future.
I want to see us colonize our solar system, maybe learn how to travel to other stars. I want to see what a post-scarcity economy might be like, if we as humans aren't too selfish to distribute wealth fairly. I want to see where medical/biological technology takes us, whether that's human cybernetics, whole-brain uploads, immersive virtual worlds, ... hell, the cures for so many diseases could be just around the corner. Man, so many possibilities, and I'm sure I'll be gone (long gone, even) before any of them becomes reality. And it's just a huge bummer to me that I won't get to experience any of it.
But hey, who knows, maybe we'll destroy ourselves via climate change, nuclear war, genocidal AI, or whatever within my lifetime. Or we'll keep sliding toward a dystopian future where 0.0001% of people live like kings and queens, and the rest of us live in miserable conditions, constantly surveilled, oppressed at every turn.
But this paper is about analyzing tissue samples from internal organs. Which is generally not what people feel when they “feel” aging. In fact most internal organs can’t be felt at all (no nerve endings), which is how people get surprised with Stage IV cancer diagnoses like pancreatic cancer.
What people generally feel are their muscles and joints are weaker and more painful. Or their eyesight gets worse. Or their digestive system works worse. And the truth is, there is a lot a person can do to adjust or mitigate these things, through simple lifestyle changes like diet and exercise.
So there is your ray of hope: you can do things differently to feel less old. Plenty of examples in the comments here.
That said, you are 100% for sure going to age and die, and there are also things you can do to help accept and prepare for that. Your body will change; your mind can change too.
That might be technically true, but I think it's worth noting that many internal organs can produce pain, e.g. kidneys, gallbladder, pancreas, prostate, urethra, stomach, intestines, bladder, heart.
E.g. a doctor will become very nervous if you report dizziness with a pain moving from your chest into your left shoulder or neck. Such pain originates along the path of the vagus nerve, which includes your lungs and heart (and half the digestive organs, and even the womb, kidneys and gall bladder sometimes). It's very tricky to diagnose, and usually extremely serious (as in ignoring it may cause death).
> And the truth is, there is a lot a person can do to adjust or mitigate these things, through simple lifestyle changes like diet and exercise.
This is spot on. I'm 46 and I've been fortunate to be healthy and in decent shape my entire life; however, a check up that was fine but trending in the wrong direction prompted these lifestyle changes.I lift run or lift daily, have reduced my carb intake significantly, stopped drinking, perform a short yoga routine each morning, and spend some time on the cushion each evening. I only wish I'd done this earlier because I feel so much better than I ever have.
I think this is bullshit. A poor lifestyle over decades will have consequences but there definitely are benefits to be had in taking up exercise and healthier eating whatever your age.
> I think this is bullshit.
At the risk of being "that guy": can we keep the temperature down? That kind of reaction feels unnecessary and is the way we get people polarized about things. (Not saying I'm not guilty of this from time to time, but I'm trying to be better!)
I was in fairly good shape and feel like, despite some grays and some crows feet, my body was relatively the same from my early 20s to my early 40s. 44 really did hit me like a ton of bricks though - working out got considerably harder, and my face started to show more permanent signs of aging, like loss of facial fat and neck banding. Can't say I was thrilled to later discover I was "right on schedule".
I am also in denial. its not just a wet place in egypt.
How's your sleep? Do you avoid eating within a couple hours of bedtime? Are you waking up to pee in the night?
I had a period when I'd drink a litre of vodka every weekend, but now it's like "one beer to chill after work". Weed is my vice though, I'm stoned every weekend. I try to cut though because the amounts I used to consume now make me tired, so I'm aiming for smaller doses.
I try to eliminate caffeine, but I keep learning about new sources of it. It's literally today that I learned just how much caffeine cola has.
Sugar is my vice definitely. I cycle every day, so I burn it. When I don't cycle I hit the gym.
Sleep... it happens often that I schedule time to sleep, I put away my phone, but then I just don't fall asleep, I just lie there awkwardly in bed. Or I wake up and then can't go back to sleep. I feel like the quality of my sleep isn't there really, which is why I decided to cut caffeine in the first place. But then I sometimes have a streak where I can sleep and function well. One thing is that I tend to get sleepy in the afternoon. If I go to bed and manage to get one full cycle of sleep, I won't feel completely miserable. I don't have big meals before bedtime but often I keep snacking on something.
Whether I wake up to pee depends on how much liquid I drink before. I'd say 50/50.
Ramen, bacon, beer, cola, weed...
Maybe cut back or eliminate those for a few weeks and see how you feel? It's obviously way easier said than done but I can almost guarantee that cleaner living will bring back some of the lost energy, and once you've got more energy it gets a lot easier to get (and stay) on track again.
Best of luck.
More seriously could be signs of depression. I felt way worse when I was depressed. Also could be something like chronic fatigue syndrome too.
P.S. get your vitamin-d levels checked. It’s a super common deficiency.
I think I've always been low-key depressed but there was always this ray of hope. But now it's dawning upon me "this is it, that's life, take it or leave it" and that's just terrifying and demotivating. I feel like I have to accept that things I wanted so bad just won't happen. And with each passing day my exhaustion keeps getting worse so I feel like the number of things that bring me joy keeps getting smaller.
msie•11h ago