That's literally the implication of these findings.
But one can always dream of a miracle drug that you can take for a bit, then stop, but its effects would stay. Evidently, Ozempic is not magical enough.
Compare that to something with no real off-ramp: testosterone replacement therapy. Once you’re on TRT, you can permanently suppress your body’s own testosterone production, and many men won’t produce enough on their own afterward.
petercooper•6m ago
You don't say ;-) I lost 50 lbs and have kept it off for the past year while maintaining great BP. But I'm under no illusions GLP-1 medications don't have dangers and cause problems for many. It should be handled on an individual basis like any serious medication.
That said, is someone losing a lot of weight then gaining half of it back worse than them just staying where they were? I don't know the answer to that one.