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Single Dose of Frog-Derived Gut Bacterium Eradicates 100% of Tumors in Mice

https://www.thefocalpoints.com/p/new-study-frog-derived-gut-bacterium
107•mpweiher•3h ago

Comments

tristanj•1h ago
Relevant xkcd: https://xkcd.com/1217/
p0w3n3d•59m ago
this one is in mice. I guess we're running in circles now.
cheschire•59m ago
Mice tumors, the scourge of humanity.
boxed•52m ago
Not really the same in this situation though.
drcongo•16m ago
As in 99.9% of cases of people who rush to the comments desperate to post a link to xkcd because, erm, actually I dunno. Why the hell do half the threads on HN have someone desperately posting an unrelated xkcd?
hootz•6m ago
It's our Nostradamus Prophecies, just like having an old Star Trek episode for everything that is happening today.
plasticeagle•22m ago
The paper states that the results are in vivo, not in vitro. The bacteria seemed to literally have cured colorectal cancer in mice. Mice are apparently strikingly similar to human beings in ways that matter, and so this research is very encouraging.

Likely too late for a particular person in my life, but hopefully not too late for others.

aa-jv•54m ago
Wow, this is humorous .. whats next, the eye of the newt cures wistfulness? I sure hope so.

Seriously though, we are living in an era where the more the science broadens its horizons, the more it just looks like plain ol' witchcraft.

I'm hoping there'll be some uses for figs we haven't thought of, next ..

vixen99•29m ago
Sure thing! Plenty of possibilities here for instance: 'Bioactive Compounds in Ficus Fruits, Their Bioactivities, and Associated Health Benefits: A Review'. (It's a pretty extensive list).

https://pdfs.semanticscholar.org/06ab/f83d30ec00bb902bb1aa37...

criddell•16m ago
You might like this episode of Radiolab:

https://radiolab.org/podcast/best-medicine

They followed a 1100 year old medicine recipe and found the resulting salve was effective against MRSA in their test.

https://pmc.ncbi.nlm.nih.gov/articles/PMC6261618/

cedws•52m ago
Bryan Johnson might be interested in IV’ing frog gut bacteria.
N_Lens•25m ago
How rude! Bryan is no labrat /j
VladVladikoff•20m ago
Is Bryan Johnson a mouse with cancer?
functionmouse•50m ago
Mice are having a great year
N_Lens•26m ago
Century*
psychoslave•13m ago
Hmm, mice get much impressive medical results to be linked to here and there, but overall it’s not certain the species benefit that much in happiness and fulfilment.
hack1312•5m ago
They told me they’re happy enough when I was delivering them cookies.
hootz•5m ago
To be honest, they are pretty cute, they don't deserve cancer.
pennomi•47m ago
The AI- generated diagram is plausible but horribly wrong the more you look at it. Thank goodness the original paper didn’t use that, it’s just this awful blog post that makes the research look like slop.
therobots927•34m ago
AGI is clearly right around the corner. It might not be able to make an accurate diagram of a cancer research study but it’s gonna cure cancer in no time…
xingped•27m ago
I wouldn't be so sure about "clearly". We're still very squarely in the "fancy auto-complete" stage of "AI", the name of which I still consider more branding than reality.
jimnotgym•37m ago
100 years of trying everything to kill bacteria, and we find they can be jolly useful
gpderetta•31m ago
humanity has been producing useful things from bacteria for thousands of things already.
degamad•29m ago
Cheese!
pestatije•27m ago
lager
usrnm•26m ago
Yeast are not bacteria, though
VladVladikoff•23m ago
Most beer until quite recently was sour from bacteria.
rimworld•30m ago
lol
ballenf•27m ago
I wonder if animals have always seen frogs as unpleasant medicine they need to eat occasionally. My dog would happily scarf them down if I let him. Or does it have to be IV administered?

Also who thinks -- "hmm we've found a new random bacteria --- let's give a bunch of tumors to mice and then IV inject this random thing into them!"?

There must have been something about the microbe that gave them a hint. Maybe it's in the cited original article and was left out of the blog post.

cyanydeez•18m ago
maybe your dog is chasing a high from some rare toad mutation...
psychoslave•15m ago
Humans can go very far in exploring all kind of variation in whatever craze they get addicted to, all the more if they get all the room and resources to do so.
petesergeant•21m ago
The blog articles (6 weeks old) describes this as new, but the linked paper is closer to 6 months old. Random report of the same bacteria giving a chemo patient sepsis: https://www.cureus.com/articles/342789-sepsis-caused-by-ewin... which seems unfortunate
degamad•13m ago
Yep, I found that one too - this paper <https://pmc.ncbi.nlm.nih.gov/articles/PMC12710904/> assumes immunocompetent mice, while the sepsis one was in a patient who was immunocompromised (both by the cancer and by chemo).

Given that many cancer sufferers are immunocompromised, this isn't necessarily a silver bullet, although it is an interesting result.

BigTTYGothGF•19m ago
Before anybody gets too excited they should check out some of the other reporting on that site, such as "COVID-19 Vaccine is the Culprit in Majority Found Dead after Injection" and "Trump Signed a Directive to Accelerate 6G Deployment to Operate "Implantable Technologies"
VMG•17m ago
Crank blog, very skeptical
tiffanyh•4m ago
To give more credit to this blog post, the NIH published findings on this same subject last year.

https://pmc.ncbi.nlm.nih.gov/articles/PMC12710904/

oofbey•3m ago
The blog is highly suspect, but the study is real. That said it’s not a big deal.

Curing cancer in a mouse model is not at all uncommon in new therapies. Mouse models like this are vastly easier to treat than real world cancer for a bunch of reasons. Fully curing mice is the baseline for a treatment to even be considered for further evaluation. And even then very few therapies end up succeeding in humans - low single digit percent.

So yes, another possible treatment. But not at all a breakthrough.

jmorenoamor•2m ago
Sorry but the site looks too sensationalist for me.

Is there any other source?

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229•pantalaimon•2h ago•47 comments

Single Dose of Frog-Derived Gut Bacterium Eradicates 100% of Tumors in Mice

https://www.thefocalpoints.com/p/new-study-frog-derived-gut-bacterium
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