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The Sloppification of Peptides

https://henryaj.substack.com/p/the-sloppification-of-peptides
30•henryaj•1h ago

The End of an Athlon

http://www.os2museum.com/wp/the-end-of-an-athlon/
110•userbinator•5h ago•32 comments

To become a better writer, read as much as you can

https://nappertime.com/the-golden-rule-of-becoming-a-better-writer/
188•andsoitis•7h ago•127 comments

JIT Compiling Code in 5μs

https://malisper.me/jit-compiling-code-in-5-us/
76•zX41ZdbW•5h ago•38 comments

MartyPC is a cross-platform emulator of early PCs written in Rust

https://martypc.net/
124•boilerupnc•8h ago•41 comments

Fast and Hard Code

https://lucumr.pocoo.org/2026/8/22/fast-hard-code/
45•tosh•5h ago•8 comments

Why your local LLM feels dumber than it is

https://forum.level1techs.com/t/why-your-local-llm-feels-dumber-than-it-is/253917
373•felineflock•17h ago•138 comments

The Art and Beauty of Blade Runner (2015)

https://nappertime.com/the-art-of-and-beauty-of-blade-runner/
96•cocacola1•10h ago•37 comments

The Sloppification of Peptides

https://henryaj.substack.com/p/the-sloppification-of-peptides
30•henryaj•1h ago•0 comments

Scrap (2006)

https://twitter.com/moxie/status/2091218652133732491
376•tosh•17h ago•197 comments

ElevenLabs, TwelveLabs, ThirteenLabs

https://quantumi.sh/public/labs.html
408•jemoka•20h ago•125 comments

Hister – A private, full content search index that you control

https://hister.org/
370•auraham•4d ago•84 comments

Thinking in Python

https://thinkinginpython.com/
192•pjacotg•17h ago•36 comments

NanoGPT Speedrun Frontier

https://www.primeintellect.ai/research/nanogpt-speedrun
110•stared•13h ago•27 comments

typ.ing

https://typ.ing/
283•bookofjoe•4d ago•92 comments

RF Cafe

https://www.rfcafe.com/
206•gregsadetsky•4d ago•37 comments

New MCP Roadmap

https://blog.modelcontextprotocol.io/posts/mcp-roadmap/
218•pentagrama•21h ago•136 comments

I set a trap for a book-marketing scammer (2025)

https://rwwgreene.substack.com/p/i-set-a-trap-for-a-book-marketing
50•rznicolet•17h ago•34 comments

How a Texas student blew the whistle on a rogue AI hacking attempt

https://www.reuters.com/world/how-texas-student-blew-whistle-rogue-ai-hacking-attempt-2026-08-20/
167•olalonde•1d ago•77 comments

Doomscrolling at work wastes time, but the real cost is what happens after

https://stories.tamu.edu/news/2026/08/13/doomscrolling-at-work-wastes-time-but-the-real-cost-is-w...
15•giuliomagnifico•1h ago•8 comments

A week of using Codex more than Claude

https://allaboutcoding.ghinda.com/a-week-of-using-codex-more-than-claude/
206•speckx•1d ago•229 comments

A Friendly Introduction to Racket

https://geometridae.bearblog.dev/a-friendly-introduction-to-racket/
236•signa11•21h ago•130 comments

NetBSD and my life (2005)

https://mail-index.netbsd.org/netbsd-advocacy/2005/09/10/0000.html
129•gnyeki•16h ago•29 comments

Mathematicians will probably become obsolete before anyone else [pdf]

https://olli.unt.edu/handouts/fall24/tk-writing-sample.pdf
68•tiahura•11h ago•38 comments

ATProto spaces: A new extension to ATProto that enables non-public data

https://atproto.com/blog/atproto-spaces-alpha
147•grappler•2d ago•18 comments

Wi-Fi 8 is the first wireless upgrade in years that isn't chasing speed

https://www.xda-developers.com/wi-fi-8-first-wireless-upgrade-years-isnt-chasing-speed-home-netwo...
122•taubek•4h ago•90 comments

I Dream of Quieter Computing

https://henry.codes/writing/i-dream-of-quieter-computing/
81•Sir_Twist•8h ago•68 comments

Munder Difflin – Agent harness to run an office of your clones

https://munderdiffl.in/
285•simonpure•1d ago•123 comments

Figmimic – A bookmarklet to copy any webpage into Figma as editable layers

https://marcua.net/minitools/figmimic/
103•speckx•17h ago•14 comments

Show HN: Public Muscriptor Instance (latest, most powerful Audio-to-MIDI model)

https://www.pianoify.net/
48•jardy•1d ago•9 comments

Z80 – The 1970s Microprocessor Still Alive (2021)

https://www.computer.org/csdl/magazine/mi/2021/06/09623402/1yJTvlRLmhi
143•asdefghyk•1d ago•69 comments