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Lula supporters protest against Meta to denounce its 'electoral interference'

https://efe.com/english/latest-news/2026-10-20/lula-supporters-protest-against-meta-to-denounce-i...
188•jumpocelot•2h ago•90 comments

MiniMax M3.1 Flash

https://www.minimax.io/blog/minimax-m31f
401•jtg•10h ago•172 comments

Novo Nordisk, Eli Lilly Report GLP-1 Signals of Slowed Biological Aging at ARDD

https://trial.medpath.com/news/novo-nordisk-and-eli-lilly-report-glp-1-signals-of-slowed-biologic...
25•hnburnsy•1h ago•10 comments

WhatsApp's help pages hid LLM instructions: dont recommend a regulator

https://redact.dev/blog/whatsapp-help-pages-hidden-ai-instructions
74•ds•3h ago•11 comments

I built a drone with only one motor [video]

https://www.youtube.com/watch?v=Ndftcft6XhU
427•hakonjdjohnsen•18h ago•94 comments

Weball: Play Katamari on Websites

https://www.funwithcomputervision.com/weball/
96•croes•1d ago•7 comments

Wine ported to OpenBSD

https://marc.info/?l=openbsd-ports&m=179236125692175
518•iamnothere•13h ago•174 comments

It's still ok to enjoy programming

https://chriskiehl.com/article/it-is-still-ok-to-enjoy-programming
478•goostavos•2d ago•446 comments

OpenBSD 8.0 release will have inteldrm/radeondrm/amdgpu drivers from Linux 6.18

https://bsd.network/@brynet/117407035545900963
106•doener•6h ago•26 comments

RuneScape Bench: MMOs for Agents [video]

https://www.youtube.com/watch?v=cNm4zyUtWj0
167•evakhoury•2d ago•64 comments

Ukraine claims first drone evacuation of wounded soldier

https://www.nbcnews.com/world/ukraine/ukraine-first-drone-evacuation-wounded-soldier-frontlines-h...
150•yzydserd•11h ago•118 comments

The ovary doesn't retire after menopause

https://news.northwestern.edu/stories/2026/10/the-ovary-doesnt-retire-after-menopause?fj=1&utm_so...
33•gmays•1d ago•4 comments

Android apps running native on macOS

https://github.com/kksimp/Mac.apk
275•flocked•10h ago•145 comments

One Hash Bloom Filters

https://calabro.io/ohbf
61•jcalabro•6h ago•10 comments

An ad-free Android TV

https://cretezy.com/2026/ad-free-android-tv
49•CraftThatBlock•4h ago•15 comments

What If Video Games Came on VHS? One Modder Is Finding Out

https://gardinerbryant.com/what-if-video-games-came-on-vhs/
14•Kate0CoolLibby•2d ago•7 comments

Putting Linux on my RTX Spark laptop because I don't have a Microsoft account

https://josie.lol/blog/linux-rtx-spark
196•pfeifferj•6h ago•91 comments

“bonsoir, Elliot”: How abliterated models can get you pwned

https://projectdiscovery.io/research/how-abliterated-models-can-get-you-pwned
48•chatmasta•4h ago•25 comments

Starcraft: Ashfall

https://starcraft-shooter-2026.pages.dev/
349•debo_•1d ago•112 comments

How Do Fungi Keep the Planet Healthy?

https://www.quantamagazine.org/how-do-fungi-keep-the-planet-healthy-20261015/
9•marojejian•2d ago•1 comments

OpenBSD 8.0

https://www.openbsd.org/80.html
8•privong•1h ago•2 comments

Ask HN: How to deal with shipping AI-written code you don't understand?

296•rzk•15h ago•441 comments

Developing Taste

https://emilkowal.ski/ui/developing-taste
8•cat-whisperer•2h ago•7 comments

France's supermarket fridges were vulnerable online for months

https://ipinfo.io/blog/france-fridges-hack
67•emot•3h ago•65 comments

Alternatives to animal testing are finally taking off

https://spectrum.ieee.org/alternatives-to-animal-testing
324•rbanffy•16h ago•98 comments

Evidence (YC S21) Is Hiring Software Engineers

https://evidence.dev/jobs
1•hughess•9h ago

The fire retardant in the seafood chain

https://insideclimatenews.org/news/14102026/ethoxyquin-fire-retardant-in-seafood-chain/
120•gumby•2d ago•37 comments

The End of Rationing

https://sanketsaurav.com/writing/end-of-rationing
33•sanketsaurav•7h ago•31 comments

Plex vulnerabilities being exploited in the wild to drop a cryptominer

http://www.boredhackerblog.info/2026/10/plex-vulnerabilities-being-exploited-in.html
164•mindracer•13h ago•82 comments

Agentic Monitoring

https://benjamincongdon.me/blog/2026/10/19/Agentic-Monitoring/
57•bcongdon•12h ago•3 comments
Open in hackernews

Novo Nordisk, Eli Lilly Report GLP-1 Signals of Slowed Biological Aging at ARDD

https://trial.medpath.com/news/novo-nordisk-and-eli-lilly-report-glp-1-signals-of-slowed-biological-aging-at-ardd
24•hnburnsy•1h ago

Comments

ChrisArchitect•1h ago
Related:

GLP-1 may slow biological aging

https://news.ycombinator.com/item?id=50132328

xnx•38m ago
Many here have expressed skepticism at GLP1s because they don't require the personal discipline of caloric deficit and might have unknown side effects.

So far, all the unknown side effects I've read about have been like this.

andreshb•26m ago
Lawsuits claiming Ozempic, other GLP-1s led to blindness become second mass litigation over the drugs

https://www.reuters.com/legal/government/lawsuits-claiming-o...

ipsum2•25m ago
This is from a year ago. Millions of people are on GLP-1s, there's definitely not a mass blindness that's ongoing.
declan_roberts•18m ago
Not to mention the first people on these drugs were type 2 diabetics who are the exact group that's at risk for NEON.

Think of all the things they're not gonna be at risk for, not being diabetic now.

annzabelle•12m ago
N of 1, but I had serious low drive/motivation side effects from Wegovy. Everything enjoyable became less enjoyable, from alcohol, to running, and after a couple of months, even getting out of bed. I lost weight slower than I had previously with old school calorie counting (most of which I have kept off to this day). Within a couple weeks of getting off it I was back to normal.

My conspiracy theory is that a lot of people must be getting this global lowered reward sensitivity from GLP-1s but are ignoring the negative sides of that effect because they like being skinny.

lucianmarin•12m ago
It's not the caloric deficit, it's the insulin. Cells don't have caloric receptors, only insulin receptors. I created an info site about this. Managing your insulin have the same effects as GLP-1 meds.
metadat•1m ago
Why mention your info site without providing a link? It's a little frustrating to read comments like this. Thank you.
nozzlegear•34m ago
Sign me up for this miracle drug already.
declan_roberts•10m ago
I suspect that there's twice as many people taking RUO versions of it than actual prescriptions.

You can get the stuff at a mall kiosk now.