frontpage.
newsnewestaskshowjobs

Open Source @Github

fp.

Open in hackernews

Claude Fable is useless for bioinformaticians

4•iqbal1980•6h ago
It’s infuriating any simple request related to common bioinformatics work and computational biology is flagged. Like we are we are trying to weaponize viruses or create anthrax!

Life science users, what’s been your experience?

Comments

roshandx•2h ago
After it returned it has become significantly dumber, I see that across Claude models maybe they applied all the inbuilt policy restrictions, I guess.
iqbal1980•1h ago
I agree!
satvikpendem•2h ago
You need to apply specifically to their program to get access to unlobotomized models. They also have a separate app here for sciences: https://claude.com/product/claude-science
iqbal1980•1h ago
Is this available for the average PhD student?
satvikpendem•7m ago
I assume it'd be through your university so you'd have to ask them or maybe email the AI companies yourself.

Ask HN: Is anyone experimenting with different ways of using LLMs for coding?

130•yehiaabdelm•19h ago•158 comments

A fleshed-out IPv5 proposal

4•bigcityslider•56m ago•2 comments

AI Is Boring

5•sverp•5h ago•5 comments

SponsorBlock Critical Security Vulnerabilities

3•IDIRIS•5h ago•3 comments

Tell HN: Fewer PRs done with proper prompting, review, and refinement wins

6•tomerbd•7h ago•3 comments

How many failed startups have you launched?

17•steelebillings•11h ago•10 comments

Cadreen – memory, governance, self-healing, and execution as one system

5•ope_john•4h ago•0 comments

Ask HN: Since when does Craigslist's front page have emojis?

38•argee•3d ago•33 comments

Ask HN: Who is hiring? (July 2026)

240•whoishiring•2d ago•296 comments

Well it's been 3 years of unemployment and $250k in debt

5•buffer_overlord•8h ago•2 comments

Ask HN: Who wants to be hired? (July 2026)

146•whoishiring•2d ago•429 comments

An AI Koan

2•rcanand2025•6h ago•0 comments

Ask HN: What did you fail at and what did you learn from it?

5•basilikum•4h ago•0 comments

Claude Fable is useless for bioinformaticians

4•iqbal1980•6h ago•5 comments

Ask HN: Why are so many "AI evangelists" posting such insufferable content?

55•seattle_spring•1d ago•32 comments

How do you test institutional (or algo) trades under real market conditions?

2•TradingReality•8h ago•0 comments

Ask HN: Procrastination with AI?

3•caprock•8h ago•1 comments

Getting Rid of Scrolling

2•matteosaporiti•9h ago•1 comments

Ask HN: Possible issue impacting AWS Cloudwatch logs availability?

2•merek•9h ago•0 comments

Ask HN: ChatGPT Go Plan

2•czeizel•5h ago•1 comments

Tell HN: Old Reddit now requires login

84•jay_kyburz•2d ago•17 comments

Tell HN: Installing Cursor on iOS irreversibly changes your privacy settings

246•zkldi•3d ago•34 comments

Ask HN: Once you make your money from vibe coding innumerable products, then?

3•keepamovin•23h ago•14 comments

Ask HN: How do you get your open-source product good traction?

5•akarshhegde18•23h ago•3 comments

Ask HN: Are any startups hiring front-end developers, or are they just using AI?

3•Kathan2651•7h ago•2 comments

Seattle Just Had an Earthquake

12•tobinfekkes•1d ago•8 comments

I'm opening VSCode less and less every day

20•othmanosx•2d ago•20 comments

Ask HN: How to Delete the HN Account?

2•_exvi•8h ago•4 comments

Burned out, how do I get out of the rut?

7•brandgefahr•1d ago•21 comments

AskHN: Using 'claude -p' for running Mr.Jassy - AWS butler agent

2•anoop_kumar•21h ago•0 comments