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How did we all miss the bacteria taking over her body?

https://www.theguardian.com/world/2025/sep/28/as-my-daughter-got-sicker-and-sicker-our-quest-for-answers-dragged-on-how-did-we-all-miss-the-bacteria-taking-over-her-body
27•atombender•1h ago

Comments

blindriver•46m ago
Seems like when doctors are confounded, then a course of strong antibiotics might be a good Hail Mary, targeting various types of bacteria. If there’s any signs of improvement then that’s a good piece of evidence to move forward in that direction.
OutOfHere•37m ago
Random strong antibiotics are not a good idea. One could estimate the possible condition, then estimate the most targeted safe antibiotic, and take it.

For example, in a specific case, for acute intestinal pain, amoxicilin with clav was being advised, but the etiology+location+correlations suggested that mere metronidazole alone would suffice, and it did. It's case by case.

wswope•3m ago
This is multiple layers of uneducated and misguided. Apart from it being a bad idea on the surface, due to antibiotic resistance and wiping out healthy parts of the microbiome, many common antibiotics have anti-inflammatory effects separate from their antimicrobial effects: https://link.springer.com/rwe/10.1007/978-3-7643-8550-7_7

Seeing someone improve after taking antibiotics is not indicative of them having an infection that’s being treated by the antibiotics.

macNchz•40m ago
For anyone interested in a deeper dive into the history and impacts of Lyme Disease I highly recommend the podcast miniseries Patient Zero: https://www.patientzeropodcast.com/
physarum_salad•37m ago
https://www.sciencedirect.com/science/article/pii/S002228362...

Bacteriophages might be an interesting approach to treating Lyme disease in future. Pretty speculative at this stage though and how do you even know the bacteria are there (as this article points out). Once detected how do you avoid the bacteriophage causing an immune reaction, etc.

physarum_salad•35m ago
Another option is to completely cover tick infested areas with suitable fungal spores: https://www.wur.nl/en/newsarticle/fungus-potential-viable-al...
OutOfHere•13m ago
Wouldn't a simple bacterial blood culture test have caught it? If not, why not? In any event, the article doesn't share which antibiotics and herbals were used.
pinkmuffinere•7m ago
The writer is clearly a good, loving parent, but this stuck out to me:

> It took weeks of careful discussion before she would try a combination of antibiotics. We didn’t yet tell her these antibiotics make some patients feel sicker.

Shouldn’t she be told the possible risks of her medication? If she was 7 i would understand, but I think she’s like 14 at this point? I guess it may be hard to determine when people can own their health decisions. But I’m upset when kids aren’t treated as “real people”, i remember being ignored because I was just a kid. I suspect that by high school almost everyone should be informed about their health decisions.

Loughla•2m ago
Informed, yes. Allowed to make critical choices as children? No.

I'm with you, people act like children don't exist when they're talking about serious matters. But you do have to remember that they lack critical reasoning (partly) and make bad choices based on hormones. Walking the line between autonomy and protection is very very very difficult as a parent. Most people struggle or fail at this, I believe.

armitron•5m ago
This is good example of how disastrous NHS can be (and it's not even that serious compared to horror stories that involve cancer) and makes me look at the flawed but also clearly superior US health system with renewed appreciation.

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