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Al Lowe on model trains, funny deaths and working with Disney

https://spillhistorie.no/2026/02/06/interview-with-sierra-veteran-al-lowe/
39•thelok•2h ago•3 comments

Hoot: Scheme on WebAssembly

https://www.spritely.institute/hoot/
101•AlexeyBrin•6h ago•18 comments

First Proof

https://arxiv.org/abs/2602.05192
52•samasblack•3h ago•39 comments

OpenCiv3: Open-source, cross-platform reimagining of Civilization III

https://openciv3.org/
789•klaussilveira•20h ago•243 comments

Stories from 25 Years of Software Development

https://susam.net/twenty-five-years-of-computing.html
39•vinhnx•3h ago•5 comments

Reinforcement Learning from Human Feedback

https://rlhfbook.com/
63•onurkanbkrc•5h ago•5 comments

The Waymo World Model

https://waymo.com/blog/2026/02/the-waymo-world-model-a-new-frontier-for-autonomous-driving-simula...
1040•xnx•1d ago•587 comments

Start all of your commands with a comma (2009)

https://rhodesmill.org/brandon/2009/commands-with-comma/
464•theblazehen•2d ago•165 comments

France's homegrown open source online office suite

https://github.com/suitenumerique
510•nar001•5h ago•235 comments

Vocal Guide – belt sing without killing yourself

https://jesperordrup.github.io/vocal-guide/
184•jesperordrup•10h ago•65 comments

Software factories and the agentic moment

https://factory.strongdm.ai/
51•mellosouls•3h ago•52 comments

The AI boom is causing shortages everywhere else

https://www.washingtonpost.com/technology/2026/02/07/ai-spending-economy-shortages/
63•1vuio0pswjnm7•7h ago•60 comments

Coding agents have replaced every framework I used

https://blog.alaindichiappari.dev/p/software-engineering-is-back
189•alainrk•5h ago•282 comments

A Fresh Look at IBM 3270 Information Display System

https://www.rs-online.com/designspark/a-fresh-look-at-ibm-3270-information-display-system
27•rbanffy•4d ago•5 comments

72M Points of Interest

https://tech.marksblogg.com/overture-places-pois.html
19•marklit•5d ago•0 comments

Unseen Footage of Atari Battlezone Arcade Cabinet Production

https://arcadeblogger.com/2026/02/02/unseen-footage-of-atari-battlezone-cabinet-production/
108•videotopia•4d ago•27 comments

Where did all the starships go?

https://www.datawrapper.de/blog/science-fiction-decline
59•speckx•4d ago•62 comments

Show HN: Look Ma, No Linux: Shell, App Installer, Vi, Cc on ESP32-S3 / BreezyBox

https://github.com/valdanylchuk/breezydemo
268•isitcontent•21h ago•34 comments

Learning from context is harder than we thought

https://hy.tencent.com/research/100025?langVersion=en
198•limoce•4d ago•107 comments

Monty: A minimal, secure Python interpreter written in Rust for use by AI

https://github.com/pydantic/monty
281•dmpetrov•21h ago•150 comments

Making geo joins faster with H3 indexes

https://floedb.ai/blog/how-we-made-geo-joins-400-faster-with-h3-indexes
152•matheusalmeida•2d ago•47 comments

British drivers over 70 to face eye tests every three years

https://www.bbc.com/news/articles/c205nxy0p31o
169•bookofjoe•2h ago•153 comments

Hackers (1995) Animated Experience

https://hackers-1995.vercel.app/
549•todsacerdoti•1d ago•266 comments

Sheldon Brown's Bicycle Technical Info

https://www.sheldonbrown.com/
422•ostacke•1d ago•110 comments

Ga68, a GNU Algol 68 Compiler

https://fosdem.org/2026/schedule/event/PEXRTN-ga68-intro/
39•matt_d•4d ago•14 comments

Show HN: I spent 4 years building a UI design tool with only the features I use

https://vecti.com
365•vecti•23h ago•167 comments

An Update on Heroku

https://www.heroku.com/blog/an-update-on-heroku/
465•lstoll•1d ago•305 comments

Show HN: If you lose your memory, how to regain access to your computer?

https://eljojo.github.io/rememory/
342•eljojo•23h ago•210 comments

What Is Ruliology?

https://writings.stephenwolfram.com/2026/01/what-is-ruliology/
66•helloplanets•4d ago•70 comments

Show HN: Kappal – CLI to Run Docker Compose YML on Kubernetes for Local Dev

https://github.com/sandys/kappal
18•sandGorgon•2d ago•8 comments
Open in hackernews

PBM Drug Pricing Distortion Report

https://www.46brooklyn.com/research/welcome-to-private-label-park-nuf485-8h5kw-wk8y2
33•toomuchtodo•2mo ago

Comments

toomuchtodo•2mo ago
Original title "This drug pricing distortion was supposed to go extinct. It’s never been more alive." reworded for context.

Mods: please feel free to update to your liking.

lotsofpulp•2mo ago
> As long-time industry researchers, we understand that drug affordability is a complicated problem with many cooks in the kitchen that can impact the end cost of a medicine.

As someone who can look up double digit profit margins for Eli Lilly/J&J/Pfizer/Novartis/Novo Nordisk/Abbvie/Merck/etc, it doesn’t look like a complicated problem.

briffle•2mo ago
you should really look up the profit margins of the largest PBM's, but they are now wholely owned by large insurance companies, or pharmacies. They are the middle men, and get a cut (and often rebates for selling over a certain amount)

https://www.drugchannels.net/2025/03/the-top-pharmacy-benefi...

TylerE•2mo ago
It's even worse than that. I have CVS for PBM and getting my prescriptions filled anywhere except a CVS will at least double the cost.
lotsofpulp•2mo ago
The profit margins of UNH/CVS/Cigna/Elevance/Humana/etc are 2% to 3%.

The PBMs are departments of these companies, hence they don’t have profit margins. Prime Therapeutics is owned by the various non profit Blues.

I don’t see how they are relevant. If they are earning more money from medicine, then it is being used to subsidize premiums.

There is a reason the market cap for almost all the pharmaceutical companies are bigger than the managed care organizations. UNH is slightly different because they sell far more high margin healthcare rather than just low margin managed care services.

w10-1•2mo ago
TLDR: Current system rewards price manipulation, resulting in vertical integration to inflate list price & reduce competition. This blog post pulls together data showing how the largest does it.

This issue has been so well-known that it has been addressed in national legislation as early as 1992 and in federal court in 2009, but the new integrated PBM's managed to sidestep regulation and transparency.

Bulk contracts specify price as a percentage of various averages (like driving contracts off LIBOR or federal funds rate), but there are few enough players and prices are private, inviting list price inflation. Contracts are not actually using federally-regulated/defined metrics (WAC, NADAC) but legacy (unregulated) AWP.

The few owners of the main PBM's (roughly matching public capital value):

- Cigna/Evernorth/Express Script: Qualient (most expansive offerings)

- CVS: Cordavis

- UnitedHealth/Optum: Nuvaila

Integrated players give themselves a discount but charge others inflated rates. The insurers might also patients charge more for going to out-of-network pharmacies. Both are relatively normal mechanisms to capture benefits of integration.

Very helpful post (but structural solutions out of scope)