it depends, our workloads can finish up in under two minutes and shut down without much effort, so we haven’t really noticed it outside of one time when we had no spot capacity.

As long as your workload can handle resuming again and your instances aren't heavily in-demand (looking at the eviction rates), the cost saving for us is substantial enough to take the occasional interruption.

I do wish Azure gave more than the 30 second eviction warning (like AWS) but still useable.