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Axios compromised on NPM – Malicious versions drop remote access trojan

https://www.stepsecurity.io/blog/axios-compromised-on-npm-malicious-versions-drop-remote-access-t...
1377•mtud•12h ago•526 comments

Open source CAD in the browser (Solvespace)

https://solvespace.com/webver.pl
79•phkahler•2h ago•18 comments

Oracle slashes 30k jobs with a cold 6 a.m. email

https://rollingout.com/2026/03/31/oracle-slashes-30000-jobs-with-a-cold-6/
85•pje•46m ago•41 comments

Combinators

https://tinyapl.rubenverg.com/docs/info/combinators
60•tosh•3h ago•11 comments

Ollama is now powered by MLX on Apple Silicon in preview

https://ollama.com/blog/mlx
472•redundantly•11h ago•231 comments

Claude Code's source code has been leaked via a map file in their NPM registry

https://twitter.com/Fried_rice/status/2038894956459290963
897•treexs•6h ago•492 comments

Artemis II is not safe to fly

https://idlewords.com/2026/03/artemis_ii_is_not_safe_to_fly.htm
599•idlewords•12h ago•372 comments

Audio tapes reveal mass rule-breaking in Milgram's obedience experiments

https://www.psypost.org/audio-tapes-reveal-mass-rule-breaking-in-milgram-s-obedience-experiments-...
98•lentoutcry•3d ago•66 comments

Multiple Sclerosis

https://subfictional.com/multiple-sclerosis/
26•luu•4d ago•8 comments

Fedware: Government apps that spy harder than the apps they ban

https://www.sambent.com/the-white-house-app-has-huawei-spyware-and-an-ice-tip-line/
624•speckx•21h ago•243 comments

Google's 200M-parameter time-series foundation model with 16k context

https://github.com/google-research/timesfm
229•codepawl•9h ago•89 comments

Universal Claude.md – cut Claude output tokens

https://github.com/drona23/claude-token-efficient
387•killme2008•13h ago•140 comments

Acceptance of entomophagy among Canadians at an insectarium

https://www.nature.com/articles/s41598-026-35288-w
9•PaulHoule•1d ago•3 comments

What major works of literature were written after age of 85? 75? 65?

https://statmodeling.stat.columbia.edu/2026/03/25/what-major-works-of-literature-were-written-aft...
51•paulpauper•2d ago•34 comments

Do your own writing

https://alexhwoods.com/dont-let-ai-write-for-you/
653•karimf•1d ago•209 comments

Good CTE, Bad CTE

https://boringsql.com/posts/good-cte-bad-cte/
121•radimm•1d ago•28 comments

30 Years Ago, Robots Learned to Walk Without Falling

https://spectrum.ieee.org/honda-p2-robot-ieee-milestone
26•vinhnx•2d ago•9 comments

GitHub backs down, kills Copilot pull-request ads after backlash

https://www.theregister.com/2026/03/30/github_copilot_ads_pull_requests/
430•_____k•10h ago•266 comments

Clojure: The Documentary, official trailer [video]

https://www.youtube.com/watch?v=JJEyffSdBsk
281•fogus•4d ago•43 comments

RamAIn (YC W26) Is Hiring

https://www.ycombinator.com/companies/ramain/jobs/jezgwo5-ai-ml-research-engineer
1•svee•8h ago

How to turn anything into a router

https://nbailey.ca/post/router/
725•yabones•1d ago•251 comments

7,655 Ransomware Claims in One Year: Group, Sector, and Country Breakdown

https://ciphercue.com/blog/7655-ransomware-claims-march-2025-to-march-2026
42•adulion•5h ago•8 comments

Android Developer Verification

https://android-developers.googleblog.com/2026/03/android-developer-verification-rolling-out-to-a...
302•ingve•17h ago•303 comments

Turning a MacBook into a touchscreen with $1 of hardware (2018)

https://anishathalye.com/macbook-touchscreen/
368•HughParry•19h ago•183 comments

In Expanding de Sitter Space, Quantum Mechanics Gets More Elusive

https://www.quantamagazine.org/in-expanding-de-sitter-space-quantum-mechanics-gets-even-more-elus...
12•pseudolus•3h ago•2 comments

Distributed data centers in our basements

9•cmos•1h ago•14 comments

We're Pausing Asimov Press

https://www.asimov.press/p/pause
75•bookofjoe•1d ago•45 comments

I Read the Leaked Claude Code Source – Here's What I Found

https://victorantos.com/posts/i-read-the-leaked-claude-code-source-heres-what-i-found/
5•victorbuilds•16m ago•1 comments

Anthropic: Claude Code users hitting usage limits 'way faster than expected'

https://www.theregister.com/2026/03/31/anthropic_claude_code_limits/
119•samizdis•3h ago•101 comments

Bird brains (2023)

https://www.dhanishsemar.com/writing/bird-brains
332•DiffTheEnder•1d ago•208 comments
Open in hackernews

Multiple Sclerosis

https://subfictional.com/multiple-sclerosis/
26•luu•4d ago

Comments

functionmouse•1h ago
Dead URL
d-us-vb•1h ago
Worked for me.
ChrisMarshallNY•57m ago
Hugged to death.

MS sucks. There’s varying degrees, though. I know folks that have it now, and ones that died from it.

Some of the treatments aren’t very nice. I knew one chap that was on Interferon, for life.

throwawaymsjs•23m ago
The modern treatments are much more effective than anybody had expected, Ocrecus went from something used in the last resort to standard care in less than a decade. I have no issue with it whatsoever though that’s not the case for everyone, and it’s now available as a 6 month injection rather than a 8+ hour infusion thankfully. The older drugs were unbelievably bad (blindness, infection, you name it), but Ocrecus has been very tame in comparison. Can’t get vaccinated for Measles (and have 0 immunity) but that’s my only limitation really.
ser13•54m ago
Archive link: https://web.archive.org/web/20260120080248/https://subfictio...
prplfsh•38m ago
https://www.astrazeneca.com/what-science-can-do/topics/next-...

AstraZeneca is doing some really interesting research in this area - cell therapies that reset the immune system to eliminate the dysfunctional cells driving autoimmune disease, and then allow a healthy immune system to rebuild (for diseases like lupus, rheumatoid arthritis, and multiple sclerosis).

konschubert•29m ago
Today, there is also AHSCT.

There are already clinics where they basically remove your immune system and give you a new one. If you don’t die in the process, you are likely to be cured of MS.

(Any existing damage will remain.)

Currently this is reserved for the most quickly progressing cases but if we can make this safer and cheaper, it might in future be applied as an early stage cure, so people can go on to live healthy lives.

That being said, Astra Zenecas approach does seem much safer, if it’s proven to be effective!

mjlee•11m ago
Anokion (now bankrupt) also seemed to have some progress along these lines (link below).

A close family member suffers from MS and is on the more effective but less safe drugs available. They haven’t suffered a relapse since starting them four years ago, but they have been hospitalised twice as a result of side effects.

As we learn more about the relationship between the immune system and various seemingly unrelated diseases the research and understanding has massively increased over the last few years. I’m cautiously optimistic that better treatments aren’t far away. An ancestor was lobotomised for hysteria in the 1960s, before being diagnosed with MS.

https://clinicaltrials.gov/study/NCT04602390