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Claude discovers a novel enzyme system with CRISPR-like repeats

https://www.anthropic.com/news/claude-discovers-novel-enzyme-system
289•raahelb•3h ago•282 comments

Fixing the Portobello Police Station Clock

https://pointinthecloud.com/2026-04-11-211700.html
326•avidly•5h ago•73 comments

Once Claude can measure something, it can make it faster

https://claude.dev/blog/how-we-made-claude-ai-faster/
87•matthieu_bl•1h ago•55 comments

Italian parliament votes for return to nuclear energy

https://apnews.com/article/italy-nuclear-chernobyl-4891b6b7c7791ae84db6b0bf0f7cf567
380•geox•4h ago•217 comments

A brief history of Windows scroll bar shortcuts

https://devblogs.microsoft.com/oldnewthing/20260922-00/?p=112719/
65•tybulewicz•3h ago•33 comments

Gemini 3.8 text-to-speech

https://blog.google/innovation-and-ai/models-and-research/gemini-models/gemini-3-8-text-to-speech/
200•swolpers•5h ago•104 comments

Radicle: Disclosure of Vulnerability in the Network Protocol

https://radicle.dev/2026/09/23/disclosure-of-vulnerability-in-network-protocol
97•lostmsu•5h ago•34 comments

Jev in 25 Lines of Python

https://www.nobodywho.ai/posts/jev-in-25-lines/
578•bashbjorn•13h ago•186 comments

LensVLM-9B by Apple

https://huggingface.co/papers/2605.07019
22•nthypes•41m ago•0 comments

Tokens too cheap to meter

https://jyn.dev/tokens-too-cheap-to-meter/
191•teoruiz•11h ago•157 comments

I don't want the details

https://michaelheap.com/i-dont-want-the-details/
298•mooreds•8h ago•175 comments

Claude Code reads AGENTS.md only when telemetry is on [fixed]

https://blog.szypowi.cz/p/claude-code-reads-agents.md-only-when-telemetry-is-on/
422•pszypowicz•9h ago•236 comments

Z80 REPL (2018)

https://abagames.github.io/z80-repl/index.html
127•adunk•10h ago•18 comments

Stripe's Knowledge AI Platform

https://stripe.dev/blog/meet-stripes-knowledge-ai-platform
153•ltononro•7h ago•97 comments

UK military jamming other nations' satellites to defend itself, BBC told

https://www.bbc.com/news/articles/c32l8y8kygdvo
98•thm•3h ago•154 comments

Show HN: Conway's Game of Life in boot sector

https://github.com/0xAX/BootLife
15•0xAX•2d ago•3 comments

Show HN: I built a post-mortem debugger for native Windows x64/x86 crashes

https://www.forensicdbg.com
9•Loren_SL•2h ago•0 comments

Swap, ZRAM, Zswap and Hibernate on NixOS

https://blog.matthewbrunelle.com/swap-zram-zswap-and-hibernate-on-nixos/
10•speckx•3h ago•2 comments

Seattle City Council votes to ban surveillance pricing in sale of groceries

https://advocacy.consumerreports.org/press_release/seattle-city-council-votes-to-ban-surveillance...
233•ortusdux•7h ago•127 comments

Show HN: An atlas of system designs with interactive architecture diagrams

https://atlas-sysdes.vercel.app/
6•mertkahyaoglu•1d ago•3 comments

QuestDB (YC S20) Is Hiring a Sales Engineer

https://questdb.com/careers/pre-sales-engineer-north-america/
1•nhourcard•9h ago

Web-based IBM 1620 emulator and IPL-V from 1963

https://github.com/pkimpel/retro-1620
35•abrax3141•21h ago•7 comments

Transit rewards

https://waymo.com/blog/2026/09/transit-rewards/
244•raybb•18h ago•308 comments

GPT-6 Sol and Luna

https://openai.com/index/introducing-gpt-6-sol-and-luna/
1724•OfficialTurkey•1d ago•819 comments

28% of job postings on company career sites have been open over 90 days

https://unlisted.careers/ghost-jobs/report/2026-09
171•rubatrejo•4h ago•256 comments

What California is learning from solar panels built over irrigation canals

https://www.kqed.org/science/2002033/heres-what-california-is-learning-from-solar-panels-built-ov...
354•Jtsummers•1d ago•682 comments

Strands Harness

https://strandsagents.com/blog/introducing-strands-harness/
120•zuckerborg0101•6h ago•88 comments

Claude Opus 5.5

https://www.anthropic.com/claude-opus-5-5
1764•km144•1d ago•1069 comments

GPT-6 Astra has gained the ability to drive a car

https://drivingbench.com/
251•plurby•6h ago•215 comments

DoorDash Spent $1.4M Trying to Stop Mamdani from Becoming Mayor. Now We Know Why

https://theintercept.com/2026/09/23/doordash-delivery-nyc-mamdani-wage-theft-settlement/
166•vrganj•1h ago•61 comments
Open in hackernews

Linear Programming for Fun and Profit

https://modal.com/blog/resource-solver
62•hmac1282•1y ago

Comments

ayhanfuat•1y ago
> X = [x1, ..., Xn]: instances of each type to launch

Is this a continuous variable? Seems discrete to me. I am surprised it is solved by simplex.

Frummy•1y ago
It's the answer, a vector of integers
ayhanfuat•1y ago
Simplex cannot give a vector of integers though, unless the constraint matrix is unimodular. Maybe the integrality constraint was relaxed.
cweld510•1y ago
You're right -- we do relax the integrality constraint, gaining performance at the expense of some precision, and we're generally able to paper over the difference at scheduling time. We've investigated integer linear programming for some use cases, but for solves to run quickly, we have to constrain the inputs significantly.
ayhanfuat•1y ago
Thanks for the clarification. I guess it wouldn’t matter much if the numbers are large. Initially I thought they were mostly ones and zeros.
stncls•1y ago
If this is business critical for you, you may want to switch to a faster solver. Glop is very nice, but it would be reasonable to expect a commercial solver (Gurobi, XPress, COpt) to be 60x faster [1]. By the same measure, the best open source solvers (CLP, HiGHS) are 2-3x faster than Glop.

Actually, the commercial solvers are so fast that I would not be surprised if they solved the IP problem as fast as Glop solves the LP. (Yes, the theory says it is impossible, but in practice it happens.) The cost of a commercial solver is 10k to 50k per license.

[1] ... this 60x number has very high variance depending on the type of problem, but it is not taken out of nowhere, it comes from the Mittelmann LP benchmarks https://plato.asu.edu/ftp/lpopt.html There are also benchmarks for other types of problems, including IP, see the whole list here: https://plato.asu.edu/bench.html

petters•1y ago
If you are able to paper over the fractional numbers and get a usable solution, an integer solver should also be able to find a feasible solution easily. Perhaps not optimal, but better than just solving the LP and rounding
hustwindmaple1•1y ago
You are basically doing a heurstic. Your solutions are not guaranteed to be optimal. Integer programming is the way to do.
cweld510•1y ago
Great to see this post here -- really enjoyed writing it! I think it's really cool how an algorithm from an operational research context can play a critical role in a high-availability large-scale cloud service.
sumtechguy•1y ago
LP is a shockingly good way to optimize a system. If you can put inputs/outputs into the correct form. Had an econ prof that loved these things for doing supply/demand maxima and minimum finding. He didnt outright say it but I think it was his current line of study when I was taking classes from him the 90s. I thought that, as he managed to bring it up in every class he taught.
Onavo•1y ago
Well, kantorovich did win the Nobel for inventing that.
underanalyzer•1y ago
Neat article. I do wish it mentioned that there are polynomial time algorithms to solve linear programming problems. According to the Google ortools docs it has the option to use those as well (but not with the GLOP solver). Might be good for when simplex is struggling (https://developers.google.com/optimization/lp/lp_advanced)
stncls•1y ago
You're right, but it's very subtle and complicated.

In theory, the simplex method is not known to be polynomial-time, and it is likely that indeed it is not. Some variants of the simplex method have been proven to take exponential time in some worst cases (Klee-Minty cubes). What solvers implement could be said to be one such variant ("steepest-edge pricing"), but because solvers have tons of heuristics and engineering, and also because they work in floating-point arithmetic... it's difficult to tell for sure.

In practice, the main alternative is interior-point (aka. barrier) methods which, contrary to the simplex method, are polynomial-time in theory. They are usually (but not always) faster, and their advantage tends to increase for larger instances. The problem is that they are converging numerical algorithms, and with floating-point arithmetic they never quite 100% converge. By contrast, the simplex method is a combinatorial algorithm, and the numerical errors it faces should not accumulate. As a result, good solvers perform "crossover" after interior-point methods, to get a numerically clean optimal solution. Crossover is a combinatorial algorithm, like the simplex method. Unlike the simplex method though, crossover is polynomial-time in theory (strongly so, even). However, here, theory and practice diverge a bit, and crossover implementations are essentially simplified simplex methods. As a result, in my opinion, calling iterior-point + crossover polynomial-time would be a stretch.

Still, for large problems, we can expect iterior-point + crossover to be faster than the simplex method, by a factor 2x to 10x.

There is also first-order methods, which are getting much attention lately. However, in my experience, you should only use that if you are willing to tolerate huge constraint violations in the solution, and wildly suboptimal solutions. Their main use case is when other solvers need too much RAM to solve your instance.

Onavo•1y ago
The most interesting question is how you scrape the prices. The cloudprovider really need to provide an API.
underanalyzer•1y ago
Very interesting! Thanks for the reply. I wonder if they tried these other solvers and decided they were either too slow b/c their problems were too small or the answers were too inaccurate