As long as I don't let myself get in a red, sunburn situation.
I've also noticed some correlation between my diet and how fast I burn. Whenever my metabolism is running at/near ketogenesis, it seems like it takes a lot longer for the sun to affect me.
6 months since i quit using nic gums.
The gene they are focusing on in the study [2] is Methylated-DNA--protein-cysteine methyltransferase (MGMT) and it needs zinc as a cofactor [3].
Not enough zinc, lower MGMT, and less DNA protection and repair.
Nutritional deficiencies and genetic differences increase the risk of cancer.
[1] https://link.springer.com/article/10.1007/s12011-023-03818-6 [2] https://www.nature.com/articles/s41586-026-10821-z [3] https://www.uniprot.org/uniprotkb/P16455/entry
That said, I'm a pretty pale dude and my sister has gotten skin cancer twice now [1], so I've started getting a bit worried that that's going to happen to me. I've started wearing a baseball cap every time I go outside to protect my scalp (since my body has decided I don't need nearly as much hair anymore), I almost never go outside without jeans and often now a hoodie even when it's relatively warm outside. If I think I'm going to be outside for more than ~30 minutes, I wear sunscreen on the exposed parts.
I have to admit, that I kind of hate it. I don't like the slimy feeling of sunscreen on my skin, I don't really like how hats feel on my head, and of course wearing a lot of clothes when it's warm outside isn't terribly comfortable.
[1] Fortunately caught very early since she gets frequent checks, so she's fine.
Also, linen clothing. Far more comfortable in heat while keeping you covered. Hoodies and jeans sounds miserable.
The more you're able to build up a base tan the less you need it too.
JoeAltmaier•1h ago
baxtr•35m ago
theoreticalmal•33m ago
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kraquepype•25m ago
manarth•6m ago
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add-sub-mul-div•21m ago
manarth•9m ago
The migration from mouse models to human understanding is long and complex, and although it's a meme, "in mice" is a good shortcut for saying "This is a good start, but it's not ready to extrapolate into conclusions against the impact to human beings".
https://www.in-mice.com/