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Ultra-processed food linked to harm in every major human organ, study finds

https://www.theguardian.com/society/2025/nov/18/ultra-processed-food-linked-to-harm-in-every-major-human-organ-study-finds
59•lentil_soup•5h ago

Comments

TheAceOfHearts•3h ago
In case anyone wants a proper definition: ultra-processed food is defined using the Nova classification system [0]. I still find the definition a bit confusing though.

This is the outcome of having researchers dedicating multiple lifetimes towards optimizing food to be as palatable and optimized as possible, such that people are forced to have a self-control battle each meal. Maybe GLP-1 drug proliferation will force companies towards other optimization goals. We ultimately end up paying for the negative externalities of UPF through higher healthcare costs and overall worse long-term quality of life.

It's difficult to change and maintain healthy eating habits when so much of your environment is designed to push you towards foods with questionable health properties. Even if it's technically possible to eat healthy, the cognitive overhead is enough that individualistic solutions are always going to be limited in effectiveness. The ideal is living in an environment where the healthy options are the default choice, so you don't have to waste time, energy, and willpower on maintenance-level tasks. I imagine that a healthier population would also be more productive, for the number-go-up optimizers.

[0] https://en.wikipedia.org/wiki/Nova_classification

_aavaa_•2h ago
My problem with it is that it’s a circular definition without a mechanism for why they are bad for health.

Discussions I’ve seen for why they are bad always basically boil down to “it’s the ingredients” without wanting to say this.

kragen•2h ago
The evidence that UPFs are bad for health is much, much stronger than the evidence for any candidate mechanism. There are lots of candidate mechanisms.

So I don't think anybody knows why they're bad. Surely the UPF classification includes lots of foods that are harmless. We just don't know which ones because we don't understand the mechanism.

_aavaa_•1h ago
If there is no understanding of mechanisms, why put such a strong emphasis on the processing, and why organize them?

I, and other people argue that it has nothing to do with the processing and it’s all about the ingredients. So the whole differentiation by “processing” amount is useless. We are talking about ingredients without wanting to say so.

sophacles•55m ago
Every time i turn on the stove my kitchen catches on fire. I can't point out whats wrong with my stove, so obviously I keep the stove in my kitchen since I can't say it's causing the fire with a specific malfunction.
jjk166•40m ago
The addition of ingredients is the processing. The different levels of processing refer to what types and quantities of ingredients are added. It's like complaining that people are labelling food as poisoned when they should really be concerned about whether it contains poison.

Likewise the categorization of processing is useful for exactly the same reason the category of poisoned is useful. I'd rather not consume poisoned food of any variety even if I'm uncertain which poison has been added to it.

mc32•1h ago
Does this mean vegetable-based replacements for meats are going to experience reduced demand given they might be worse for health and more expensive than their meat counterparts?

They certainly meet the ultra processed foods criterion.

UncleMeat•51m ago
Right but this is one of the major challenges with converting this information into actionable nutritional advice.

We have this (reasonably) rigid definition that grants the appearance of specificity. But there are almost surely UPFs that are fine and there are probably non-UPFs that cause the same problems as UPFs. Potato chips are hyper palatable, but are not UPFs.

So what is the benefit of saying "avoid UPFs" over "avoid junk food?" At least saying "avoid junk food" makes the fuzziness apparent. But by focusing on this UPF definition (which is almost surely not the actual thing that is causing negative health outcomes) we end up in weird scenarios where potato chips and bean-to-bar chocolate are fine but wheat bread with preservatives are not even if it turns out that the preservatives aren't the source of any problem.

threatofrain•1h ago
Explanation is the goal of science but description is the foundational step. If one can arbitrarily use a marker and draw a circle around a demographic, and thereby generate predictions which correspond with empiricism, then you have the beginning of a useful term.

So if it turns out that south-east Asians who immigrate to the US experience a bad risk of diabetes, then we've already engaged in useful empiricism despite being short of "why".

general1465•2h ago
Yeah the whole definition is bogus. i.e. "mechanically separated meat" is considered ultraprocessed food? Why? By this logic putting apples into mixer and creating pyre is ultraprocessed food too.
_aavaa_•2h ago
And even if you want to define it as such, why is that bad for health?
zug_zug•1h ago
It’s bad for health because the science says so.

You’re welcome to do your own years of research to learn more (everything, cooking, freezing, drying, blending, adding acids affects amino acids and certainly bacteria in the food) but until then stick with what the studies prove

JoeAltmaier•1h ago
I guess a reasonable person can question the science, when ordinary words are used wildly inappropriately. E.g. 'ultra-processed' to mean things that are far from that.

If 'the science' is so conclusive, then maybe a single link to a single study would be an appropriate response.

zug_zug•26m ago
How about responding to the one in the article…?
UncleMeat•46m ago
The science is messy.

The UPF definition includes a ton of very distinct things. It is unlikely that emulsifiers, preservatives, food dyes, added sugar, and removed fiber all produce the same health responses. Science showing correlations between UPF consumption and health outcomes also don't tend to show a dose response, which is odd. We'd expect lots of UPF consumption to be very bad and for some UPF consumption to be kind of bad, but we don't tend to see this in the data.

Nutritional research is also enormously difficult to perform. Any sort of controlled study is necessarily over short periods of time. Long term studies come with all of the messy confounds that make it remarkably difficult to determine causation.

zug_zug•23m ago
The one in the article is dose dependent…

And I really don’t understand your point at all. All science starts with observing a correlation and deducing a cause years to centuries later.

But you don’t wait for newton to start believing in gravity

Lord-Jobo•1h ago
Tangent because I do think you are asking a pretty clear question, but I find it’s much more helpful in these discussions to specify why(mechanical explanation) from why(elaborate on known info) from why(what is the human reason for an action).

Because you really can interpret any of these in a lot of the situations where someone is asking “why”.

metalman•1h ago
it's not food,thats why

it is a food substitute. food is composed of recognisable ingedients. what comes from factorys has no connection or relation to that. the unspoken premise is that pre prepared stuff with a label is somehow part of a continuity. , pared= to cut/divided

prepared=cut/divided~for you

pre prepared= wtf?

_aavaa_•1h ago
What are you talking about? Why is it not food?
Jensson•1h ago
> it's not food,thats why

Its pure meat, meat is food. What do you mean?

stephen_g•1h ago
I’ve seen one theory that it might be something to do with not needing as much chewing and how quickly you can eat it. I can’t remember exactly the article I was reading but apparently there is a massive difference (e.g. insulin spike, etc.) eating apple purée of one apple vs. eating an apple.

Needing to chew less processed food may help just by being kind of rate-limiting (slowing down how fast you can get the food in), but also the enzymes in your saliva have time to start working on the food before you swallow it.

If I recall correctly I have also read (perhaps the same article, but maybe somewhere else) that some processes related to digestion might be triggered when you start eating (chewing), so the fact that you can eat so many calories so quickly before those processes get going might make a big difference too.

lentil_soup•1h ago
as I understand, it's also the fiber. The fiber acts as a barrier that slows down the speed at which you absorb the food which leads to a smoother insulin spike (in case of carbs) and a faster feeling of satiation. When you blend the apple all that fiber is broken down do it loses those properties
macNchz•1h ago
Does anybody eat mechanically separated meat as-is? I imagine it’s basically only available to end users as a final product like chicken nuggets or hot dogs, mixed with many additives.
glitchc•1h ago
So the additives are unhealthy?
macNchz•41m ago
I don’t think anybody has a concrete answer yet, I’ve seen speculation that the texture of the food may be a component, and the extreme palatability that causes people to eat more than they otherwise would. There are so many potential root causes that it will take time to pinpoint specific ones, but what is becoming clear that eating lots of foods with additives and highly altered basic ingredients (like mechanically separated meat) is not good for you.
glitchc•9m ago
I have a hard time understanding how the act of mechanically separating meat from bone and gristle renders it unfit for consumption. Texture certainly matters for taste, but once masticated, all food is roughly the same texture. Digestion is a biochemical process, and if the body is experiencing adverse reactions to certain foods, the cause should be a biochemical one.
Jensson•1h ago
You never ate ground meat? It is very common to buy separated processed meat without other ingredients since it is very quick and easy to cook.
macNchz•57m ago
Mechanically separated meat is different from ground meat, it’s made by pressing unusable scraps through a sieve to remove bits of bone. The end result is a paste.
general1465•1h ago
It is available as ground meat. You can make meatloaf from it. Or you can buy preformed meatballs which is just ground meat with some shape so you can just drop it into pan and bake in the oven. 40 minutes and done.

Peel some potatoes, cook them and you have a dinner in said 40 minutes.

And I have no idea why this would be classified as ultraprocessed food.

SPICLK2•47m ago
Is such "ground meat" labelled differently from ground or minced meat that is made the traditional way?
macNchz•20m ago
In the US at least they are considered different things and must be labelled as such.
macNchz•17m ago
Ground meat is different from mechanically separated meat, which is a paste. At least personally I haven’t seen ground meat for sale in the US that lists MSM as an ingredient, though it may exist.
htek•57m ago
Those identically shaped chicken, turkey and ham for slicing at the deli are generally mechanically separated.
throwaway89201•1h ago
I'm not sure you are replying knowing what "mechanically separated meat is", as it isn't just cutting / separating pieces of regular meat using machinery. It's the sieving of a ground up bone/flesh mix into a meat paste. The result product is not something you would normally call meat, and called 'white slime' by some.
lentil_soup•1h ago
Apples are actually a great example.

Think of eating an apple vs drinking apple juice. The amount of entire apples you can drink is immense compared to eating the apple whole. So the mechanical process does affect how we consume the food.

mr_mitm•12m ago
If you are asking the question whether UPF is bad, surely you got to control for the amount. Of course you can say that people tend to eat too much of UPF simply because it is easier to prepare and eat, but that doesn't mean it's the processing that is bad for you. It's still just the amount.
Concrete3286•59m ago
Seems like a reasonable definition? It's not referring to tissue you put through a grinder yourself.

From wikipedia:

Mechanically separated meat (MSM), mechanically recovered/reclaimed meat (MRM), or mechanically deboned meat (MDM) is a paste-like meat product produced by forcing pureed or ground beef, pork, mutton, turkey or chicken under high pressure through a sieve or similar device to separate the bone from the edible meat tissue. When poultry is used, it is sometimes called white slime as an analog to meat-additive pink slime and to meat extracted by advanced meat recovery systems, both of which are different processes. The process entails pureeing or grinding the carcass left after the manual removal of meat from the bones and then forcing the slurry through a sieve under pressure.

The resulting product is a blend primarily consisting of tissues not generally considered meat, along with a much smaller amount of actual meat (muscle tissue).

UncleMeat•50m ago
But what's the issue? I can eat beef and beef tendon separately but if they are blended together it suddenly becomes bad?
jhallenworld•48m ago
I always assumed ultra-processed means that the food is loaded with preservatives like phosphates or BHT. I guess that's part of it, but maybe the efficiency of digestion should be considered. I remember Ben Krasnow (Applied Science) measured the calories in poop, humans are not very efficient at extracting all calories leading to very likely large efficiency variance between foods. But extending this further, the calories lost during preparation should be accounted for...

So how about: calories * digestion-efficiency - calories you personally need to expend to prepare or acquire it. The higher this number, the more processed is the food. So cane sugar is very bad, unless you personally harvested it.

Bad news for highly paid programmers.. basically all food should be considered ultra-processed since no physical labor was needed to acquire it.

iammjm•2h ago
Weird choice of the image by TheGuardian: there's some obviously highly processed foods such as doughnuts and candy, but you also have french fries, popcorn and even some nuts there. The text itself doesn't elaborate on this much either. What is it exactly that I am supposed to avoid?
Lord-Jobo•1h ago
The easy answer that encompasses 99% of the target foods is:

Avoid any foods that involve multiple rounds of processing, a term that includes baking, frying, adding preservatives,sugars or oils. Generally, if it has a lot of sugar or oil and has a weirdly long shelf life, be suspicious.

Drift towards: easily washable (smooth/peelable) fruits and vegetables, 100% whole wheat bread products, simple meat products like whole animal parts or deboned animal parts.

Dairy lives in the middle ground. If you have zero lactose problem, most dairy is mostly okay, just watch for sugar levels and recognize that most dairy products are calorie dense. Nuts are in this group too for the same reason but oil instead of sugar.

Bonus points for consuming real pro and pre biotics when you can. In the United States this is pretty limited to live culture yogurts, refrigerated kimchi, and refrigerated sourkraut.

Jensson•1h ago
Popcorn is just 1 round of cooking though, you can fry them yourself at home, its less processing than bread.
glitchc•1h ago
Hang on. Pickling and fermentation are multi-step processes to transform food into their final state. Moreover, pickling is expressly used for preservation and long shelf life. Why are they not considered "ultra-processed" according to this definition? As you point out, they are an integral part of a healthy diet in multiple cultures.
z500•51m ago
What's wrong with baking?
AdmiralAsshat•1h ago
> but you also have french fries, popcorn and even some nuts there

For popcorn at least, I'd assume it's the prepackaged microwavable popcorn that gets flagged as UPF, where it's encased in hydrogenated oils, salt, and preservatives. It's hard to think that popcorn you make at home could be considered UPF, considering that it's literally one ingredient with heat applied to it (and oil I guess if you're popping it on the stovetop rather than an air fryer).

randerson•52m ago
Microwave Popcorn containers are also coated with PFAs.
zug_zug•19m ago
Yeah ever heard of popcorn lung? Crazy stuff
skeezyjefferson•1h ago
why was this flagged?

imagine just buying normal food that wasnt done on the cheap. nobody could afford to live. even in usa, richest country in the world, people are eating cheap crap, living in wooden houses... of course you can be the richest country in the world if you just lower your living standards perpetually

moi2388•52m ago
I buy normal food and it’s plenty cheap tbh
ranger_danger•50m ago
Probably because "ultra-processed" is a bogus definition that doesn't prove what exactly is unsafe or why, which the authors of the study even acknowledge directly in the article:

> Critics argue UPF is an ill-defined category and existing health policies, such as those aimed at reducing sugar and salt consumption, are sufficient to deal with the threat.

> Monteiro and his co-authors acknowledged valid scientific critiques of Nova and UPF – such as lack of long-term clinical and community trials, an emerging understanding of mechanisms, and the existence of subgroups with different nutritional values.

It's not "processing" in itself that is causing problems, there is something specific (possibly a set of common ingredients used in many such foods) that we just haven't identified yet as what the actual harm is, so people lump all processed food into the harmful category and tell people to just stay away from all of it, which is not a realistic solution given current food production practices.

zug_zug•14m ago
Sounds like those people are having an irrational emotional response to a term rather than addressing the presented research in good faith.

Also being a broad or nebulous category doesn’t make it not science… much of what science studies starts broad and nebulous or even theoretical.

iammjm•44m ago
dafuq is "normal" food? if by normal you mean usual or typical for a supermarket, then that would be mostly highly processed foods full of sugars and fats. Now that I think about it, what one actually wants is the not-normal foods, the raw unprocessed minority
Isamu•1h ago
Discussion about this tends to get hung up on the relative harm of a particular food, let’s say a donut. But the article is really about a diet that is dominated by food like donuts.

>Evidence reviewed by 43 of the world’s leading experts suggests that diets high in UPF are linked to overeating, poor nutritional quality and higher exposure to harmful chemicals and additives.

>This category is made up of products that have been industrially manufactured, often using artificial flavours, emulsifiers and colouring. They include soft drinks and packaged snacks, and tend to be extremely palatable and high in calories but low in nutrients.

>They are also designed and marketed to displace fresh food and traditional meals, while maximising corporate profits, Monteiro said.

WesolyKubeczek•1h ago
Is there some clear boundary where a food stops being just processed and starts to be ultraprocessed?

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